Identification of five newly described bioactive chemical compounds in methanolic extract of Mentha viridis by using gas chromatography - mass spectrometry (GC-MS)

Abstract

The bioactive compounds were screened by gas chromatography-mass spectrometry (GC-MS) method. Twenty one bioactive phytochemical compounds were identified in the methanolic extract of Mentha viridis using GC-MS method. The identification of phytochemical compounds is based on the peak area, retention time, molecular weight and molecular formula. GC-MS analysis of M. viridis revealed the existence of the 3,6-Octadecadiynoic acid, methyl ester, 2,5-Dimethyl-4-hydroxy-3(2H)-furanone, 4Hpyran-4-one, 2,3-dihydro-3,5-dihydroxy-6-methyl, benzofuran, R-Limonene, 2-methoxy-4-vinylphenol, 2hydroxy-5-methylbenaldehyde, tetra-acetyl-d-xylonic nitrile, Ficusin, Phen-1,4-diol, 2,3-dimethyl-5trifluoromethyl, n-Hexadecanoic acid, 7-Methyl-Z-tetradecen-1-ol acetate, Ethyl 9,12,15octadecatrienoate, Methyl 19-methyl-eicosanoate, Ethyl iso-allocholate, and Tocopherol. Five new bioactive chemical compounds 3-(N,N-Dimethyllayrylammonio), 1b,4a-eboxy-2H-cyclopenta [3,4]cyclopropal [8,9] cycloundec, 5H-Cyclopropa[3,4]benz [1,2-e]azulene-5-one, 2,2,4-Trimethyl-3-(3,8), 12,16-tetramethyl-hepta deca, and 4H-Cyclopropa[5,6]benz [1,2:7,8] azulene[5,6-b] oxiren-4-one are described and may in future be suitable sources for phytotherapy purposes. Mentha viridis contain chemical constitutions which may be useful for various herbal formulation exhibiting cardiac tonic, analgesic, antiasthamatic, anti-inflammatory and antipyretic properties.

GC-MS Analysis of Phytochemical Constituents from Ethyl Acetate and Methanol Extract of Artocarpus altilis (Parkinson) Fosberg from Endau Rompin, Johor, Malaysia

“…The compound is the most common longchain saturated fatty acid that is naturally produced by the wide range of plants, animals, and microorganisms. The compound was found in the literature to possess vast bioactivity such as antibacterial, anti-inflammatory, anti-fungal [2,17], antioxidant [23], pesticide, antioxidant, hypocholesterolemic nematicide and 5-Alphareductase inhibitor [17,24]. Furthermore, hexa-A B decanoic acid was recently reported to poses cytotoxic activities against cancer cell lines [5,17,26].…”

“…The compound was found in the literature to possess vast bioactivity such as antibacterial, anti-inflammatory, anti-fungal [2,17], antioxidant [23], pesticide, antioxidant, hypocholesterolemic nematicide and 5-Alphareductase inhibitor [17,24]. Furthermore, hexa-A B decanoic acid was recently reported to poses cytotoxic activities against cancer cell lines [5,17,26]. Thus, the effective anti-proliferative activities demonstrated by the selected crude extracts in this study might be contributed by the synergistic effect of this compound with the other compounds identified.…”

The antimicrobial and antioxidant property, GC–MS analysis of non-edible oil-seed cakes of neem, madhuca, and simarouba

“…Hence, Candida albicans is a clinical pathogen capable of causing infections that persist for a long time in humans (Calderone and Clancy 2012). (Dharni et al 2014), antibacterial activity (Dehpour et al 2012;Aissaoui et al 2019), antioxidant and anticancer (Choi et al 2013), herbicidal (Halim et al 2017) Madhuca (cold) 0.13 Thymol Madhuca (cold) 0.21 Antibacterial, antifungal, antioxidant, antiseptic, antitumor, anti-inflammatory, anti-hyperlipidaemia (Marchese et al 2016) 7-Methyl-Z-tetradecen-1-ol acetate Madhuca (cold) 0.52 Anticancer, anti-inflammatory, hepatoprotective (Hameed et al 2015) Chloramben, methyl ester Madhuca (cold) 0.12 Herbicide (Wehtje et al 1992) Nonanal Simarouba (cold) 0.99 Antibacterial (Bisignano et al 2001), Antifungal (Zhang et al 2017) Antidiarrheal (Miguel et al 2008) VasudhaUdupa et al Bull Natl Res Cent (2021 The cyclic voltammetry is a powerful electrochemical technique employed to investigate the reduction and oxidation potential of molecular species (Suliborska et al 2019). This method correlated with the antioxidant assays by chemical and spectrometric means (Martinez et al 2006;Keffous et al 2016).…”

Microbial biofilm inhibition, antioxidants, and chemical fingerprints of Afghani pomegranate peel extract documented by gas chromatography–mass spectrometry and Fourier transformation infrared

“…The pomegranate peel extract was investigated for bioactive compounds using GC-MS (QP 2010 Plus SHIMADZU, Japan) tool under computer control at 70 eV (Imad et al, 2015). GC-MS micro injects was used to scan the 1 μl of n-hexane peel extract for 45 min by maintaining the oven temperature up to 100℃.…”