Identification of Volatile Components and Antioxidant Assessment of the Aerial Part Extracts from an Algerian Cistus Albidus L. of the Aures Region

Fadel, Hamza; Kebbi, Sara; Jean-claude, Chalchat; Figuérédo, Gilles; Cartigny, Pierre; Benayache, Fadila; Ghedadba, Nabil

doi:10.12816/0058534

Cited by 4 publications

(5 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This is mainly because the analytical methods described are not suitable for detecting non-volatile substances and not because of the absence of these compounds. The diterpenes detected so far are geranyl linalool, geranyl α-terpinene, geranyl p-cymene and 13-epi-mannoyloxide [ 53 ], methyl neoabietate [ 47 ], 15,16-dinorlabd-8(20)-en-13-one, manool [ 106 ], and manoyl oxide [ 126 ]. The latter was found in the aerial parts, including the stems, unlike 15,16-dinorlabd-8(20)-en-13-one and manool, which were obtained only from the leaves.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…Although fatty acids are products of the primary metabolism, they are described here for the role they may play in the bioavailability of pharmacologically active compounds, as described below. Among the fatty acids found in the aerial parts of C. albidus are tetradecanoic, primaric and pentadecanoic acid [ 47 ], nonanoic acid [ 106 ], palmitic acid [ 53 ], and butanoic acid [ 49 ]. The fatty acid composition of the seeds showed significantly higher levels of polyunsaturated fatty acids as well as very-long-chain saturated fatty acids for older plants due to their higher levels of linoleic acid [ 27 ].…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…The fatty acid composition of the seeds showed significantly higher levels of polyunsaturated fatty acids as well as very-long-chain saturated fatty acids for older plants due to their higher levels of linoleic acid [ 27 ]. In addition, the carboxylic acids methacrylic acid [ 106 ] and quinic acid [ 12 , 177 ] were identified.…”

Section: Phytochemical Constituentsmentioning

confidence: 99%

“…analgesic, antinociceptive [55]; antimicrobial, antiviral [56]; anticancer [57]; antitussive [58]; [29] n/a dant [46,48,49]. analgesic, antinociceptive [55]; antimicrobial, antiviral [56]; anticancer [57]; antitussive [58]; skin penetration enhancer [59]; Carene polycyclic monoterpene hydrocarbon 🌱✿ [52] antiviral [60]; enhances bone mineralization [61]; anti-inflammatory [62]; Carvacrol monocyclic monoterpene alcohol 🌱✿ [49] antibacterial (64); antifungal [63]; antioxidant [64]; anticancer [65]; anti-inflammatory, analgesic [66]; antiobesity [67]; hepatoprotective [68]; spasmolytic [69]; vasorelaxant [70]; β-Cyclocitral oxygenated monocyclic monoterpene 🌱 [53] n/a [106] antioxidant, anti-inflammatory [166]; anticancer [167]; antihypertensive [168]; cardioprotective [169];…”

Section: Nomentioning

confidence: 99%

See 3 more Smart Citations

Cistus albidus L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential

Raus de Baviera,

Ruiz-Canales,

Barrajón-Catalán

2023

Plants

View full text Add to dashboard Cite

Cistus albidus L. (Cistaceae) is a medicinal plant that has been used therapeutically since ancient times in the Mediterranean basin for its important pharmacological properties. The ability of C. albidus to produce large quantities of a wide range of natural metabolites makes it an attractive source of raw material. The main constituents with bioactive functions that exert pharmacological effects are terpenes and polyphenols, with more than 200 identified compounds. The purpose of this review is to offer a detailed account of the botanical, ethnological, phytochemical, and pharmacological characteristics of C. albidus with the aim of encouraging additional pharmaceutical investigations into the potential therapeutic benefits of this medicinal plant. This review was carried out using organized searches of the available literature up to July 2023. A detailed analysis of C. albidus confirms its traditional use as a medicinal plant. The outcome of several studies suggests a deeper involvement of certain polyphenols and terpenes in multiple mechanisms such as inflammation and pain, with a potential application focus on neurodegenerative diseases and disorders. Other diseases such as prostate cancer and leukemia have already been researched with promising results for this plant, for which no intoxication has been reported in humans.

show abstract

Section: Phytochemical Constituentsmentioning

confidence: 99%

Section: Phytochemical Constituentsmentioning

confidence: 99%

Section: Phytochemical Constituentsmentioning

confidence: 99%

Section: Nomentioning

confidence: 99%

See 2 more Smart Citations

Cistus albidus L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential

Raus de Baviera,

Ruiz-Canales,

Barrajón-Catalán

2023

Plants

View full text Add to dashboard Cite

show abstract

“…The plant has enjoyable biological activities, including antioxidant, anti-inflammatory, and antimicrobial activity (Haouat et al, 2013;Bouyahya et al, 2016;Fadel et al, 2020). These effects are mainly attributed to its chemical composition rich in secondary metabolites.…”

Section: Introductionmentioning

confidence: 99%

Chemical profiling of volatile compounds of the essential oil of grey-leaved rockrose (Cistus albidus L.) and its antioxidant, anti-inflammatory, antibacterial, antifungal, and anticancer activity in vitro and in silico

Elbouzidi,

Taibi,

Laaraj

et al. 2024

Front. Chem.

View full text Add to dashboard Cite

Cistus albidus: L., also known as Grey-leaved rockrose and locally addressed as šṭab or tûzzâla lbîḍa, is a plant species with a well-established reputation for its health-promoting properties and traditional use for the treatment of various diseases. This research delves into exploring the essential oil extracted from the aerial components of Cistus albidus (referred to as CAEO), aiming to comprehend its properties concerning antioxidation, anti-inflammation, antimicrobial efficacy, and cytotoxicity. Firstly, a comprehensive analysis of CAEO’s chemical composition was performed through Gas Chromatography-Mass Spectrometry (GC-MS). Subsequently, four complementary assays were conducted to assess its antioxidant potential, including DPPH scavenging, β-carotene bleaching, ABTS scavenging, and total antioxidant capacity assays. The investigation delved into the anti-inflammatory properties via the 5-lipoxygenase assay and the antimicrobial effects of CAEO against various bacterial and fungal strains. Additionally, the research investigated the cytotoxic effects of CAEO on two human breast cancer subtypes, namely, MCF-7 and MDA-MB-231. Chemical analysis revealed camphene as the major compound, comprising 39.21% of the composition, followed by α-pinene (19.01%), bornyl acetate (18.32%), tricyclene (6.86%), and melonal (5.44%). Notably, CAEO exhibited robust antioxidant activity, as demonstrated by the low IC50 values in DPPH (153.92 ± 4.30 μg/mL) and β-carotene (95.25 ± 3.75 μg/mL) assays, indicating its ability to counteract oxidative damage. The ABTS assay and the total antioxidant capacity assay also confirmed the potent antioxidant potential with IC50 values of 120.51 ± 3.33 TE μmol/mL and 458.25 ± 3.67 µg AAE/mg, respectively. In terms of anti-inflammatory activity, CAEO displayed a substantial lipoxygenase inhibition at 0.5 mg/mL. Its antimicrobial properties were broad-spectrum, although some resistance was observed in the case of Escherichia coli and Staphylococcus aureus. CAEO exhibited significant dose-dependent inhibitory effects on tumor cell lines in vitro. Additionally, computational analyses were carried out to appraise the physicochemical characteristics, drug-likeness, and pharmacokinetic properties of CAEO’s constituent molecules, while the toxicity was assessed using the Protox II web server.

show abstract

Synthesis, pharmacological and molecular docking investigations of 1,3,4-oxadiazole-5-thionyl derivatives of extracted cis-clerodane diterpenoid from Cistus monspeliensis

et al. 2022

View full text Add to dashboard Cite

Identification of Volatile Components and Antioxidant Assessment of the Aerial Part Extracts from an Algerian Cistus Albidus L. of the Aures Region

Cited by 4 publications

References 29 publications

Cistus albidus L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential

Cistus albidus L.—Review of a Traditional Mediterranean Medicinal Plant with Pharmacological Potential

Chemical profiling of volatile compounds of the essential oil of grey-leaved rockrose (Cistus albidus L.) and its antioxidant, anti-inflammatory, antibacterial, antifungal, and anticancer activity in vitro and in silico

Synthesis, pharmacological and molecular docking investigations of 1,3,4-oxadiazole-5-thionyl derivatives of extracted cis-clerodane diterpenoid from Cistus monspeliensis

Contact Info

Product

Resources

About