RSC Chem. Biol.
 2024
DOI: 10.1039/d3cb00214d
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Identifying ligands for the PHD1 finger of KDM5A through high-throughput screening

Gloria Ortiz,
James E. Longbotham,
Sophia L. Qin
et al.

Abstract: PHD fingers are a type of chromatin reader that primarily recognize chromatin as a function of lysine methylation state. Dysregulated PHD fingers are implicated in various human diseases, including acute...

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