Idiopathic eruptive macular pigmentation with papillomatosis

Abstract

We present a case of an otherwise healthy 10-year-old girl who presented with asymptomatic brown macules over the trunk and proximal extremities, of three months’ duration. The cutaneous examination revealed multiple, dark brown, discrete, round to oval macules and a few mildly elevated lesions over the trunk and proximal limbs. The individual lesion was 1-3 cm in diameter and a few showed velvety appearance over the surface. Darier's sign was negative. The histopathological study from the velvety lesion showed acanthosis, papillomatosis and increased melanin in the basal layer. The upper dermis showed sparse perivascular infiltrate of lymphocytes without any dermal melanophages. It fulfilled the criteria for idiopathic eruptive macular pigmentation with additional histological finding of papillomatosis.

Idiopathic eruptive macular pigmentation in an Indian male

“…[ 7 ] Emphasis has been laid on the histological presence of pigmented papillomatosis to be a diagnostic criteria for IEMP [ Table 1 ]. [ 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 ]…”

Idiopathic Eruptive Macular Pigmentation: A Rare and an Under-reported Entity

“…IEMP is a rare under-reported skin disorder which is now regarded as the clinical reminiscent of acanthosis nigricans lesions [5][6][7]. After careful review of the pertinent literature till date, less than 50 cases of IEMP have been documented worldwide with handful of them being reported from India [1,5,6,[8][9][10][11][12]. The largest series of 10 cases has been published by Jang KA et al from Korea [13].…”

Idiopathic eruptive macular pigmentation in a pediatric patient and a review of the literature

“…Morphology included tan to dark brown as a descriptor in 33 cases, macules in 33 cases, and patches in 6 cases. [4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Biopsy 15 The underlying pathogenesis for IEMP remains unclear and several theories have been proposed. There may be a hormonal influence as it tends to present in children and adolescents most commonly during puberty.…”