Idiopathic Hypoparathyroidism

Paravertebral and peripheral ligamentous ossification: an unusual association of hypoparathyroidism

“…The patient here described and those reported by Biischer (1948), Salvesen and Boe (1953), Gibberd (1965) and Chaykin et al (1969) had symptoms and clinical signs which closely resembled those found in patients with ankylosing spondylitis. In addition, all had marked limitation of movement of hip and shoulder joints but without evidence of arthritis affecting the small joints.…”

“…The association has been reported in idiopathic and post-operative hypoparathyroidism (Biuscher, 1948; Salvesen and Boe, 1953;Gibberd, 1965;Chaykin, Frame and Sigler, 1969).…”

Autoimmune Polyglandular Syndrome Type 1

“…In collaboration with Prof. O. Kämpe (University of Uppsala) we tested 51-kDa Abs by IPA in 15 APS type 1 patients, and 10 (66%) were positive. There was no association between the 51-kDa protein autoantibodies and ICA or GAD 65 Abs. Five patients were followed-up for a mean period of 8 yr. None developed IDDM.…”

“…However, ICA were found in 12 of 40 (30%) patients without IDDM; the majority of them were also positive for GAD 65 Abs. In collaboration with Prof. O. Kämpe (University of Uppsala) we tested 51-kDa Abs by IPA in 15 APS type 1 patients, and 10 (66%) were positive.…”

“…Malabsorption: Malabsorption and/or steatorrhea have been described in patients with APS type 1 since 1953 (63,65), with a prevalence of 18 -22% (5, 6). Malabsorption can be due to a variety of causes, one of which is coeliac disease, as reported since 1955 (66).…”