Idiopathic scrotal calcinosis: A case series

Andola, Sainath K; Karangadan, Shabnam; Patil, Suresh S.

doi:10.4103/2349-6029.147312

Cited by 5 publications

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“…Two of them gave a history of white chalky discharge from the nodules. 5 of the cases presented with single nodules, ranging in size from 0.5 to 3 cm (mean 1.89 cm) [10]. In our study, 3 of the cases presented with multiple nodules (60%) and the largest nodule measured 3 cm in diameter.…”

Section: Discussionmentioning

confidence: 41%

“…Few patients may present with swelling, heaviness, pruritis, ulceration and white chalky discharge [9]. SC is a benign lesion of the skin however it may mimic epidermal inclusion cyst, steatoma or other benign tumors, such as solitary neurofibroma, lipoma and fibroma [10]. In study by Andola, which included 9 patients, the majority of the cases presented with scrotal swelling (8/9) and were clinically diagnosed with sebaceous cysts (7/9).…”

Section: Discussionmentioning

confidence: 99%

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Scrotal Calcinosis: Analysis of 5 Cases

et al. 2018

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Idiopathic scrotal calcinosis (ISC) is an uncommon benign process, characterized by solitary or multiple, painless, strict scrotal nodules in the lack of systemic metabolic disorder. Its nature and reason have remained unknown and theories of origin contain idiopathic calcification arising within normal scrotal collagen, dystrophic calcification of inflamed scrotal epidermoid cysts, eccrine duct milia or dartoic muscle, and secondary to minor trauma. A total of 5 cases were found for ISC in our department of pathology. All patients underwent surgical excision of the lesions with overlying skin. Age range was from 25 to 49 years with a mean age of 31.4 years. Three of the patients with multiple lesions (3/5). The common appearance of the masses were hard, slowly growing, semi-mobile, lobulated, and well-circumscribed subcutaneous nodules. Diameter of the lesions ranged 0.7cm to 3cm. Grossly, there were firm, white with chalky and gritty areas. H&E stains revealed basophilic masses in dermis with foreign body giant cell reaction in 4 cases. No recurrences were noted. ISC is a rare, benign, disease of the scrotal skin that is characterized by calcium depositions of various sizes surrounded by a granulomatous reaction. In spite of the debate about the origin of this entity, surgery still seems to be the treatment of option and provides a good clinical outcome.

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Section: Discussionmentioning

confidence: 41%

Section: Discussionmentioning

confidence: 99%

Scrotal Calcinosis: Analysis of 5 Cases

et al. 2018

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“…Aún se ignora su etiopatogénesis, varios autores postulan el lento adelgazamiento y eventual desaparición del recubrimiento epitelial de la pared del aparato folicular y la formación de pequeños quistes de inclusión epidérmica, al fragmentarse por estímulos irritativos externos en personas susceptibles, que permiten la salida de la queratina hacia la dermis circunvecina con su consecuente calcificación y respuesta inflamatoria resultante 8 . Por el contrario, otros autores plantean la hipótesis de que la calcinosis escrotal podría ser originada por la degeneración del músculo dartos 9 .…”

Section: Discussionunclassified

Calcinosis escrotal idiopática: Reporte de un caso.

Bouquett

Sánchez

2022

Investigación Clínica

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Calcium participates in many physiological processes. Calcinosis cutis is a disease caused by calcium deposition in the dermis. Idiopathic scrotal calcinosis (ICS) is a common form of idiopathic calcinosis cutis. A 28-year-old male patient was evaluated, with symptoms of multiple white masses in the scrotum, of various sizes, not painful. Calcium and phosphorus levels were with-in normal ranges, characteristic of idiopathic calcinosis, while vitamin D and PTH were outside the normal limits. Minor surgery was performed on circum-scribed nodular lesions of various sizes with regular borders. Post-biopsy histo-logical examination confirmed the diagnosis of calcinosis cutis. A low-calcium diet was prescribed as a long-term preventive method. Despite the infrequency of this condition, it should be taken into account when making a differential diagnosis. Its etiology is still unknown and it can present asymptomatically. The important thing is to provide the patient with a better quality of life, avoid discomfort and low self-esteem due to the aesthetic aspect.

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“…Some authors believe that these nodules are because of dystrophic calcification in a background of epidermal inclusion cysts, or calcification secondary to trauma. 5 Few studies found the peculiar pathological pattern of cysts (Pilar or epidermal), with calcification of keratinous material with in the lumen. No cyst lining was observed in older lesion, as a result of enlargement of cyst and attenuation of cyst wall.…”

Section: Discussionmentioning

confidence: 99%

Idiopathic scrotal calcinosis: A brief case report

Panhotra¹,

Hassan²,

Sehgal³

et al. 2020

ACHR

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Idiopathic Scrotal Calcinosis (ISC) is a rare benign lesion involving the scrotal skin which is characterized by the presence of single or multiple calcified nodules. It usually presents during third decade of life. Many theories about the etiopathogenesis have been proposed, one of which is dystrophic calcification in the background of epidermal inclusion cyst over a period of time. Clinically, scrotal calcinosis may be confused with epidermal inclusion cysts, steatocystoma, cutaneous circumscription or benign tumors like lipoma, fibroma or others. Our patient, 25 year old male presented with multiple painless swellings over scrotal skin. Clinical diagnosis of multiple sebaceous cysts was made. Surgical excision of all the nodules was done and sent for histopathological examination. Microscopy revealed presence of amorphous basophilic calcified deposits in the dermis, predominantly without epithelial lining. The histopathological diagnosis of idiopathic scrotal calcinosis was made.

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Idiopathic scrotal calcinosis: A case series

Cited by 5 publications

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Scrotal Calcinosis: Analysis of 5 Cases

Scrotal Calcinosis: Analysis of 5 Cases

Calcinosis escrotal idiopática: Reporte de un caso.

Idiopathic scrotal calcinosis: A brief case report

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