“…Numerous studies have, however, found that healthy high school and university students use methylphenidate to improve concentration, alertness and academic performance, or for recreational purposes. 2,3,4,5 The term 'non-medical use' of prescription drugs is defined by the United Nations Office on Drugs and Crime as the taking of prescription drugs, whether obtained by prescription or otherwise, other than in the manner or for the reasons or time period prescribed, or by a person for whom the drug was not prescribed. 6 In contrast, offlabel use in the United States (US) implies that the regulations of the Food and Drug Administration (FDA) permit physicians to prescribe approved medications for other than their intended indications, and misuse refers to the wrong, improper use or misapplication.…”