Image guidance to improve reliability and data integrity of transcranial Doppler sonography

Neulen, Axel; Greke, Christian; Prokesch, Esther; König, J.; Wertheimer, Daniel; Giese, Alf

doi:10.1016/j.clineuro.2012.12.025

Cited by 9 publications

(1 citation statement)

References 20 publications

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“…It is highly unlikely that this outcome is due to the NovaGuide system as it is an effective tool for acquiring MCA CBFv. Some studies have documented that even highly trained sonographers can have difficulty in correctly identifying the MCA, misidentifying it as often as 40% of the time 17 . However, in the study by O’Brien et al the NovaGuide matched the efficacy in MCA signal acquisition of a registered vascular technician (RVT) on 86 healthy subjects with a mean velocity accuracy of 99.7% (95% CI 97.7%–101.7%) with respect to the RVT.This investigation also showed a mean time to signal acquisition of 74.4 s (95% CI 60–90 s) and a no-window rate of 3.5% (RVT no-window rate was 4.1%) 18 .…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of a novel robotic transcranial doppler system in subarachnoid hemorrhage

Clare

Stein

Damodara

et al. 2022

Sci Rep

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Delayed cerebral ischemia (DCI) secondary to vasospasm is a determinate of outcomes following non-traumatic subarachnoid hemorrhage (SAH). SAH patients are monitored using transcranial doppler (TCD) to measure cerebral blood flow velocities (CBFv). However, the accuracy and precision of manually acquired TCD can be operator dependent. The NovaGuide robotic TCD system attempts to standardize acquisition. This investigation evaluated the safety and efficacy of the NovaGuide system in SAH patients in a Neuro ICU. We retrospectively identified 48 NovaGuide scans conducted on SAH patients. Mean and maximum middle cerebral artery (MCA) CBFv were obtained from the NovaGuide and the level of agreement between CBFv and computed tomography angiography (CTA) for vasospasm was determined. Safety of NovaGuide acquisition of CBFv was evaluated based on number of complications with central venous lines (CVL) and external ventricular drains (EVD). There was significant agreement between the NovaGuide and CTA (Cohen’s Kappa = 0.74) when maximum MCA CBFv ≥ 120 cm/s was the threshold for vasospasm. 27/48 scans were carried out with CVLs and EVDs present without negative outcomes. The lack of adverse events associated with EVDs/CVLs and the strong congruence between maximal MCA CBFv and CTA illustrates the diagnostic utility of the NovaGuide.

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Section: Discussionmentioning

confidence: 99%