Image guided radiation therapy for bladder cancer: Assessment of bladder motion using implanted fiducial markers

Biancia, Cesar Della; Yorke, Ellen

doi:10.1016/j.prro.2013.07.008

Cited by 15 publications

(18 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was found that the results of the fiducial match on kV CBCT were comparable to the same match on kV 2D images [17].…”

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 58%

“…All studies reported some degree of fading or washout of Lipiodol spots throughout the course of treatment with the exception of Meijer et al [14][15][16]18,20,21] (Table III). Seed loss was also reported by all studies during treatment, ranging from 2% to 41%, when assessed on various imaging modalities (MV CBCT, kV CBCT and kV 2D images) [17,19,22]. In the case of the Garcia et al study, this 2% loss was reported only for gold seeds not placed in the tumor area.…”

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 79%

“…Possible target displacements of up to 13.5 mm and 16.8 mm in the anterior direction and superior directions, respectively, when using a bony match compared to a fiducial match, were demonstrated [17]. The evidence for the use of fiducial marker registration is promising; however, the level of evidence provided is poor as these results are based on one observational study with 20 participants.…”

Section: Discussionmentioning

confidence: 99%

“…Lipiodol and fiducial matching are also appropriate for specialized techniques, such as IMRT and adaptive radiotherapy [14,17,18,21]. The superior set-up accuracy has translated into margin reduction, organ at risk sparing and also partial bladder treatment.…”

Section: Discussionmentioning

confidence: 99%

“…Considering the difference in set-up errors between using gold fiducial marker image registration and a bony match registration, on both kV two-dimensional (2D) and kV CBCT imaging (Table I), Della Biancia et al reported increased accuracy when using fiducial match compared to a bony match, on kV CBCT [17]. It was found that the results of the fiducial match on kV CBCT were comparable to the same match on kV 2D images [17].…”

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 99%

See 4 more Smart Citations

A review of the use of fiducial markers for image-guided bladder radiotherapy

Nolan

Forde

2015

Acta Oncologica

View full text Add to dashboard Cite

Background: Enhancing target visualization and reducing set-up errors in image-guided radiotherapy (IGRT) are issues faced when trying to implement more conformal and partial bladder techniques. This review examines the evidence available pertaining to the clinical use of Lipiodol and gold fiducials for IGRT for bladder cancer. Material and methods: Nine published articles relating to the feasibility of using Lipiodol injections or gold fiducial markers in IGRT for bladder patients were recruited from a database search strategy. Set-up errors were evaluated in addition to the stability and visibility of each on verification imaging. Adverse reactions from the insertion of each method were also assessed. Results: Both Lipiodol and gold fiducials have the potential to remain stable and visible in the bladder, however, fading, washout and seed loss was also reported. Set-up errors can be reduced by using Lipiodol or fiducial registration when compared to other registration techniques. Adverse reactions reported were minimal for each. Conclusion: Current evidence suggests that Lipiodol injections and gold fiducial markers present as promising and highly accurate methods of overcoming interfraction bladder motion in IGRT.

show abstract

“…It was found that the results of the fiducial match on kV CBCT were comparable to the same match on kV 2D images [17].…”

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 58%

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 79%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Impact On Reducing Set-up Errors and Enhancing Image Registrmentioning

confidence: 99%

See 3 more Smart Citations

A review of the use of fiducial markers for image-guided bladder radiotherapy

Nolan

Forde

2015

Acta Oncologica

View full text Add to dashboard Cite

show abstract

Retrospective evaluation of planning margins for patients undergoing radical radiation therapy treatment for bladder cancer using volumetric modulated arc therapy and cone beam computed tomography

Dower

Ford

Sandford

et al. 2021

J of Medical Radiation Sci

View full text Add to dashboard Cite

Introduction: Current contouring guidelines for curative radiation therapy for muscle-invasive bladder cancer (MIBC) recommend margins of 1.5-2.0 cm, applied to the clinical target volume (CTV). This study assessed whether the use of volumetric modulated arc therapy (VMAT), cone beam computed tomography (CBCT) and strict bladder preparation allowed for a reduced planning target volume (PTV) expansion, resulting in lower doses to surrounding organs at risk (OARs). Methods: Daily CBCT images for 12 patients (382 scans total) were retrospectively reviewed against four potential PTV margins created on and exported with the reference CT scan. To form the PTVs, three isotropic expansions of 0.5, 1.0 and 1.5 cm were applied to the CTV, as well as an anisotropic expansion of 1.5 cm superiorly and 1.0 cm in all other dimensions. Following treatment completion, the CBCTs were visually assessed to determine the margins encapsulating the bladder. For retrospective planning purposes, the 1.0-cm and anisotropic margins were compared with the previously recommended margins to determine differences in OAR doses. Results: The 0.5-, 1.0-and 1.5-cm isotropic margins (IM) and the anisotropic margin (ANIM) covered the CTV in 46.1, 96.8, 100 and 100% of CBCTs retrospectively. Doses to OARs were significantly lower for the reduced margin plans for the small bowel, rectum and sigmoid. Conclusion: Bladder planning target volumes may be safely reduced. We endorse a PTV margin of 1.0cm anteriorly, posteriorly and inferiorly with 1.0-1.5 cm superiorly for radical whole bladder cases using strict bladder preparation, VMAT and pretreatment CBCTs.

show abstract