Image-guided radiation therapy: what is our Utopia?

Beavis, A W

doi:10.1259/bjr/26132255

Cited by 6 publications

(2 citation statements)

References 10 publications

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“…This idea was used in the analysis of daily position corrections by pre-treatment MVCT imaging for patients with prostate cancer and simulation of the residual errors if the no-action-level protocol was applied. 73,74 The adaptive procedure based on the online set-up correction enabled Piziorska et al 75 to reduce the PTV margin to 7, 7 and 4 mm for the vertical, longitudinal and lateral directions, respectively.…”

Section: Use Of Daily Ultrasoundmentioning

confidence: 99%

Target margins in radiotherapy of prostate cancer

Yartsev

2016

BJR

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We reviewed the literature on the use of margins in radiotherapy of patients with prostate cancer, focusing on different options for image guidance (IG) and technical issues. The search in PubMed database was limited to include studies that involved external beam radiotherapy of the intact prostate. Post-prostatectomy studies, brachytherapy and particle therapy were excluded. Each article was characterized according to the IG strategy used: positioning on external marks using room lasers, bone anatomy and soft tissue match, usage of fiducial markers, electromagnetic tracking and adapted delivery. A lack of uniformity in margin selection among institutions was evident from the review. In general, introduction of pre- and in-treatment IG was associated with smaller planning target volume (PTV) margins, but there was a lack of definitive experimental/clinical studies providing robust information on selection of exact PTV values. In addition, there is a lack of comparative research regarding the cost-benefit ratio of the different strategies: insertion of fiducial markers or electromagnetic transponders facilitates prostate gland localization but at a price of invasive procedure; frequent pre-treatment imaging increases patient in-room time, dose and labour; online plan adaptation should improve radiation delivery accuracy but requires fast and precise computation. Finally, optimal protocols for quality assurance procedures need to be established.

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Section: Use Of Daily Ultrasoundmentioning

confidence: 99%

Target margins in radiotherapy of prostate cancer

Yartsev

2016

BJR

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“…Changes to the composite delivered dose and their impact on disease control as well as toxicity may be minimized by use of appropriate localization devices and planning target volume (PTV) margins. Occasionally, re-planning may be required if gross deviations beyond predetermined tolerances are observed [1][2][3].…”

Section: Igrt -The Conceptmentioning

confidence: 99%

Image Guided Radiation Therapy

Kataria¹

2014

J Nucl Med Radiat Ther

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With increasing emphasis on reducing the volume of radiation therapy fields while maintaining or improving precision of treatment and reducing radiation-related normal tissue toxicity, treatment position verification and correction before delivering radiotherapy had gained major importance. A variety of techniques have been developed that can accomplish this goal with aplomb, albeit each with its own set of limitations. The best method that eliminates uncertainties in treatment without a huge cost remains to be defined, but it is clear that carrying out "high precision radiotherapy" without periodic image guidance is as accurate as shooting in a dark room. This review discusses the concept of image guidance in radiotherapy, various techniques available along with expected benefits and pitfalls of these systems.

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Magnetic resonance image guidance in external beam radiation therapy planning and delivery

et al. 2017

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The use of magnetic resonance (MR) imaging in radiation oncology is improving dramatically. This review article discusses the necessity of image guidance and how MR finds a significant place in radiotherapy planning and delivery. The challenges to and current solutions for an in-house MR simulation, dedicated MR simulator, estimation of electron density using MR image sets and development of MR-compatible treatment planning systems are presented. This article also reviews the feasibility, advantages and limitations of MR image-guided radiation therapy (MR-IGRT) and its drive toward the integration of radiation beams with MR technology. Specifications of Co-60 MR technology and three other MR-linac projects worldwide are presented. Online and real-time MR guidance is also discussed.

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Image-guided radiation therapy: what is our Utopia?

Cited by 6 publications

References 10 publications

Target margins in radiotherapy of prostate cancer

Target margins in radiotherapy of prostate cancer

Image Guided Radiation Therapy

Magnetic resonance image guidance in external beam radiation therapy planning and delivery

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