Imaginal disc growth factor is involved in melanin synthesis and energy metabolism in <i>Bombyx mori</i>

Tian, Huan; Liu, Shuai-Qi; Jing, Wenhui; Hao, Zhihua; Li, Yinghui; Lu, Zhe-Hao; Ding, Ze-Kai; Huang, Shujun; Xu, Ye; Wang, Huabing

doi:10.1002/arch.21995

Cited by 2 publications

(3 citation statements)

References 55 publications

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“…The IL-17 signaling pathway (oas04657) regulates the production and action of IL-17, which can inhibit melanin production [135]. Purine metabolism (oas00230) may be associated with golden pigment production [136][137][138], which correlates with the blue phenotype [139], and may also affect melanin synthesis [140][141][142]. Glycine, serine, and threonine metabolism (oas00260) also correlate with the blue phenotype [139,143].…”

Section: Go Terms and Pathways Associated With Non-white Woolmentioning

confidence: 99%

Whole Genome Resequencing Reveals Selection Signals Related to Wool Color in Sheep

Zhang,

Jin,

et al. 2023

Animals

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Wool color is controlled by a variety of genes. Although the gene regulation of some wool colors has been studied in relative depth, there may still be unknown genetic variants and control genes for some colors or different breeds of wool that need to be identified and recognized by whole genome resequencing. Therefore, we used whole genome resequencing data to compare and analyze sheep populations of different breeds by population differentiation index and nucleotide diversity ratios (Fst and θπ ratio) as well as extended haplotype purity between populations (XP-EHH) to reveal selection signals related to wool coloration in sheep. Screening in the non-white wool color group (G1 vs. G2) yielded 365 candidate genes, among which PDE4B, GMDS, GATA1, RCOR1, MAPK4, SLC36A1, and PPP3CA were associated with the formation of non-white wool; an enrichment analysis of the candidate genes yielded 21 significant GO terms and 49 significant KEGG pathways (p < 0.05), among which 17 GO terms and 21 KEGG pathways were associated with the formation of non-white wool. Screening in the white wool color group (G2 vs. G1) yielded 214 candidate genes, including ABCD4, VSX2, ITCH, NNT, POLA1, IGF1R, HOXA10, and DAO, which were associated with the formation of white wool; an enrichment analysis of the candidate genes revealed 9 significant GO-enriched pathways and 19 significant KEGG pathways (p < 0.05), including 5 GO terms and 12 KEGG pathways associated with the formation of white wool. In addition to furthering our understanding of wool color genetics, this research is important for breeding purposes.

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Section: Go Terms and Pathways Associated With Non-white Woolmentioning

confidence: 99%

Whole Genome Resequencing Reveals Selection Signals Related to Wool Color in Sheep

Zhang,

Jin,

et al. 2023

Animals

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“…For example, Group V chitinases are associated with Imaginal Disk Growth Factors (IDGFs) and play roles in insect eclosion, antimicrobial activity, innate immunity, cell division, and energy balance. [8][9][10][11][12] Chitinase 6 (Cht6), belonging to Group VI chitinases, plays a role in wing cuticle development in Drosophila melanogaster. 13 Group VII chitinase 2 (Cht2) influences chitin content, which forms the cuticle and impacts insect growth and development.…”

Section: Introductionmentioning

confidence: 99%

“…Group V to Group VII chitinases also play pivotal roles in insect physiology. For example, Group V chitinases are associated with Imaginal Disk Growth Factors ( IDGF s) and play roles in insect eclosion, antimicrobial activity, innate immunity, cell division, and energy balance 8–12 . Chitinase 6 ( Cht6 ), belonging to Group VI chitinases, plays a role in wing cuticle development in Drosophila melanogaster 13 .…”

Section: Introductionmentioning

confidence: 99%

Effect of four chitinase genes on the female fecundity in Sogatella furcifera (Horváth)

Zeng,

Gong,

Yang

et al. 2023

Pest Management Science

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BACKGROUNDThe white‐backed planthopper (WPH), Sogatella furcifera (Horváth), is a destructive rice pest with strong reproductive capacity. To gain insights into the roles of chitinases in the reproductive process of this insect species, this study represents the first‐ever endeavor to conduct an in‐depth exploration into the reproductive functions of four chitinase genes.RESULTSIn this study, it was observed that four chitinase genes were expressed in female adults, with a relatively high expression level in the ovaries. SfCht2 and SfIDGF1 were highly expressed during later ovarian development. while SfENGase increased and then decreased with ovarian development. SfCht2, SfCht6‐2 and SfENGase were highly expressed in fat body on the first and second days after eclosion, whereas SfIDGF1 highest on day 7. Compared with control group, Silencing four chitinase genes inhibited ovarian development and significantly shortened the oviposition period of S. furcifera, reducing egg‐laying capacity but not affecting egg hatching. The detection demonstrated that the expression levels of SfVg, SfVgR and 70–90% juvenile hormone (JH) signaling pathway‐related reproductive genes was significantly down‐regulated. Moreover, SfCht6‐2 and SfENGase significantly affected the expression levels of Target of Rapamycin (TOR) signaling pathway genes. SfENGase had the ability to impact nutrient signaling pathways and fatty acid metabolism, repressing vitellogenin synthesis and ultimately influencing ovarian development of S. furcifera.CONCLUSIONSOverall, this study provides insight into the function of chitinases in insect fecundity and is of great significance for enriching the cognition of insect chitinase function. They will become the suitable target genes for controlling the most destructive rice planthoppers. © 2023 Society of Chemical Industry.

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Imaginal disc growth factor is involved in melanin synthesis and energy metabolism in Bombyx mori

Abstract: The imaginal disc growth factor (IDGF), belonging to the glycoside hydrolase 18 family, plays an important role in various physiological processes in insects. However, the detail physiological function of IDGF is still unclear. In this

Cited by 2 publications

References 55 publications

Whole Genome Resequencing Reveals Selection Signals Related to Wool Color in Sheep

Whole Genome Resequencing Reveals Selection Signals Related to Wool Color in Sheep

Effect of four chitinase genes on the female fecundity in Sogatella furcifera (Horváth)

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