Imaging and histomorphometric evaluation of mandible and tibia of rats treated with bisphosphonates

Martelli, S; Damian, Melissa Feres; Schinestsck, André Ribeiro; Schuch, Lauren Frenzel; Cascaes, Andréia Morales; Vasconcelos, Ana Carolina Uchôa

doi:10.1007/s10006-019-00807-9

Cited by 4 publications

(2 citation statements)

References 27 publications

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“…The information on the density of the alveolar bones has a practical relevance, for example, in dental implant treatment planning, where local bone quality is known to be a strong predictor of successful implant osseointegration [4,5]. Various attempts were made to assess or analyze bone density using CBCT images [6][7][8][9][10][11][12][13]. Studies reported that the voxel values of CBCT images were generally not as accurate for representing bone density as those of general clinical CT images [14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

A Comparative Study on the Voxel Values in Alveolar Bones Acquired by MDCT and Newly Developed Dental Dual-Energy CBCT

Chang¹,

Lee²

2021

Sensors

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The purpose of this study was to analyze the effectiveness of newly developed dental dual-energy (DE) cone-beam computed tomography (CBCT) to compare both the voxel values in hard bone tissue of DE-CBCT and multidetector computed tomography (MDCT) images, collected in a clinical trial conducted at Seoul National University Dental Hospital. A software implemented as a scripted module of a three-dimensional (3D) slicer was developed to register the volume data from the MDCT space to DE-CBCT, locate the same 3D regions of interest (ROIs) in each image space, and extract the statistics of the ROIs. The mean values were paired and used as representative values of the ROIs. A scatter plot with the line of equality and Bland–Altman (BA) plot of difference for a pair of measured means were used for statistical analysis. Of the ROI pairs, 96% were within ±15% from the identity line, and more than 95% of the measured ROI pairs were within the limits of agreement of the 95% confidence intervals (CIs), with the CI of the limits in BA plots. The newly developed dental DE-CBCT showed a level of voxel value accuracy similar to that of MDCT.

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Section: Introductionmentioning

confidence: 99%

A Comparative Study on the Voxel Values in Alveolar Bones Acquired by MDCT and Newly Developed Dental Dual-Energy CBCT

Chang¹,

Lee²

2021

Sensors

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“…To date, scarce clinical data are available regarding the association between the bone quality measured by CBCT and the histomorphometric findings. Studies involving animal experiments [9] or human carcasses [10] have provided the initial findings.…”

Section: Introductionmentioning

confidence: 99%

Associations among Primary Stability, Histomorphometric Findings, and Bone Density: A Prospective Randomized Study after Alveolar Ridge Preservation with a Collagen Cone

et al. 2020

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Background: The objective of this investigation was to examine whether determination of bone density (BD) with a cone beam computed tomography (CBCT) scan could help predict the primary stability (PS) of the implants and to investigate whether associations between the histomorphometric findings and the CBCT scan could be observed. Materials and methods: In this randomized clinical study, the efficacy of alveolar ridge preservation (ARP) with a combination of a collagen cone and a collagen membrane procedure after tooth extraction was investigated. CBCT scans were obtained after a healing period of 8 (±1) weeks. Subsequently, the CBCT scans were evaluated in terms of BD at different heights of the former socket. Eleven (±1) weeks after tooth extraction, implant placement was performed and PS was measured with resonance frequency analysis. Potential associations among the radiologically measured BD, the histomorphometric results, and the PS were analyzed. Results: No direct association was observed between the radiologically determined BD and the histomorphometric findings. No significant associations could be found between the BD and the PS. Conclusion: No significant associations were observed among the BD determined by the CBCT, the histomorphometric findings, and the PS.

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Influence of the cumulative effect of zoledronic acid on periodontal microcirculation in rats

Kosach

Petrosyan

Yaremenko

et al. 2021

Oral Maxillofac Surg

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Imaging and histomorphometric evaluation of mandible and tibia of rats treated with bisphosphonates

Cited by 4 publications

References 27 publications

A Comparative Study on the Voxel Values in Alveolar Bones Acquired by MDCT and Newly Developed Dental Dual-Energy CBCT

A Comparative Study on the Voxel Values in Alveolar Bones Acquired by MDCT and Newly Developed Dental Dual-Energy CBCT

Associations among Primary Stability, Histomorphometric Findings, and Bone Density: A Prospective Randomized Study after Alveolar Ridge Preservation with a Collagen Cone

Influence of the cumulative effect of zoledronic acid on periodontal microcirculation in rats

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