1990
DOI: 10.1016/1047-8477(90)90098-w
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Imaging cells with the atomic force microscope

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Cited by 256 publications
(109 citation statements)
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“…Soon after its invention, AFM became a valuable tool for imaging cells (Butt et al, 1990;Radmacher et al, 1992). However, AFM imaging of single cells requires their firm attachment to a surface, which is not always a simple task.…”
Section: Imaging Living Cells With Afmmentioning
confidence: 99%
“…Soon after its invention, AFM became a valuable tool for imaging cells (Butt et al, 1990;Radmacher et al, 1992). However, AFM imaging of single cells requires their firm attachment to a surface, which is not always a simple task.…”
Section: Imaging Living Cells With Afmmentioning
confidence: 99%
“…We have examined the transmitter release face surface topography and distribution of calcium channels by atomic force microscopy (AFM) applied to the calyx-type presynaptic nerve terminal of the chick ciliary ganglion. AFM is a surface topography scanning technique with nanometer resolution that, in contrast to electron microscopy, can be used to scan hydrated biological samples (Henderson et al, 1992;Parpura et al, 1993aParpura et al, , 1993bButt et al, 1990;Hoh et al, 1991;Hoh and Hansma, 1992). Most nerve terminals are of such small size that, once isolated in a hydrated state, their surfaces are high ly curved and difficu It to study in detail with a contact scanning technique such as AFM.…”
Section: Introductionmentioning
confidence: 99%
“…Cell fixation by glutaraldehyde is often used to simplify the study of cells and to improve imaging resolution [934]. Cell fixation is a process where cells are treated with different agents, e.g.…”
Section: Filled Polyelectrolyte Capsulesmentioning
confidence: 99%