2023
DOI: 10.1186/s12987-023-00499-0
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Imaging the neurovascular unit in health and neurodegeneration: a scoping review of interdependencies between MRI measures

Ella Rowsthorn,
William Pham,
Mohammad-Reza Nazem-Zadeh
et al.

Abstract: The neurovascular unit (NVU) is a complex structure that facilitates nutrient delivery and metabolic waste clearance, forms the blood–brain barrier (BBB), and supports fluid homeostasis in the brain. The integrity of NVU subcomponents can be measured in vivo using magnetic resonance imaging (MRI), including quantification of enlarged perivascular spaces (ePVS), BBB permeability, cerebral perfusion and extracellular free water. The breakdown of NVU subparts is individually associated with aging, pathology, and … Show more

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Cited by 9 publications
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