Imaging the Ocular Anterior Segment With Real-Time, Full-Range Fourier-Domain Optical Coherence Tomography

Sarunic, Marinko V.

doi:10.1001/archopht.126.4.537

Cited by 92 publications

(73 citation statements)

References 39 publications

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“…In addition to the retinal imaging that is the most popular application of OCT, an anterior segment OCT (AS-OCT) has also been developed to observe the morphometric properties of the anterior eye segment. The technique of the interferometer for AS-OCT was translated from time-domain OCT [2] into spectraldomain OCT and swept-source OCT (SS-OCT) or optical frequency domain imaging (OFDI) [3][4][5][6][7] because of advantages in the sensitivity [8][9][10] and ability of high-speed imaging [11,12].…”

Section: Introductionmentioning

confidence: 99%

Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment

Yamanari

Tsuda

Kokubun

et al. 2015

Biomed. Opt. Express

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Abstract:We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment. 37. B. Braaf, K. A. Vermeer, M. de Groot, K. V. Vienola, and J. F. de Boer, "Fiber-based polarization-sensitive OCT of the human retina with correction of system polarization distortions," Biomed.

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Section: Introductionmentioning

confidence: 99%

Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment

Yamanari

Tsuda

Kokubun

et al. 2015

Biomed. Opt. Express

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“…Possible applications to optometry such as contact lens fit to and its movement on the eye surface were demonstrated by video-rate and three-dimensional imaging performed with the spectral optical coherence tomography [37]. New tunable light sources have been reported for anterior segment OCT imaging [38][39][40][41][42].…”

Section: Introductionmentioning

confidence: 99%

Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Grulkowski¹,

Gora²,

Szkulmowski³

et al. 2009

Opt. Express

154

124

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Abstract:We describe a new ultrahigh speed Spectral OCT instrument making use of a CMOS camera and demonstrate high quality in vivo imaging of the anterior segment of the human eye. The high flexibility of the designed imaging system allows a wide range of imaging protocols. Two-and three-dimensional high quality OCT images of the cornea, the anterior chamber and the crystalline lens are presented. A high acquisition rate, up to 135,000 A-scans/second enables three-dimensional reconstruction of the anterior segment during lenticular accommodation, blinking and pupillary reaction to light stimulus. We demonstrate OCT tomographic real time imaging of the lens dynamics during accommodation and high quality OCT cross-sectional images of the entire anterior segment of the eye from the cornea up to posterior part of the crystalline lens. 2009 Optical Society of America

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“…[4][5][6] Sometimes a symmetric overlapping image artefact, referred to in literature as the complex conjugate or mirror image artefact, can show up in OCT images. 7,8 However, a healthy retina is much thinner than 2 mm and, by keeping the patient's retina completely on one side of the reference position, this artefact will normally not show up in the scans of the posterior segment. An example of the mirror image artefact is shown in Figures 2a and b, showing a mirroring of the inner layer of the retinoschisis.…”

Section: Eyementioning

confidence: 99%

“…7,[9][10][11] In addition to TD-OCT systems (Visante, Zeiss; Anterior Segment OCT, Heidelberg, Germany), a dedicated anterior segment FD OCT system is now commercially available (Casia SS-1000, Tomey Corporation, Nagoya, Japan). 12,13 Commercially available posterior segment OCT systems can also be modified to take scans of the anterior segment.…”

Section: Eyementioning

confidence: 99%

Scanning beyond the limits of standard OCT with a Fourier domain optical coherence tomography integrated into a slit lamp: the SL SCAN-1

Stehouwer

Verbraak

Vries

et al. 2010

Eye

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Purpose With a new Fourier domain optical coherence tomography (FD OCT) device, SL SCAN-1 (Topcon Europe Medical BV, Capelle a/d IJssel, The Netherlands), integrated into a slit-lamp OCT, scans can be obtained through a handheld lens. The necessary adjustment of the reference arm is possible by fast Z-alignment. This study was performed to prove the capability of SL SCAN-1 to scan through a three-mirror contact lens, scanning the peripheral retina and anterior chamber angle. Methods Different representative pathologies of the peripheral retina and anterior chamber were simultaneously observed and scanned with the SL SCAN-1. The scans of peripheral retinal lesions were obtained both through a handheld lens and through a three-mirror contact lens. The anterior chamber angle was scanned directly with the SL SCAN-1 in anterior mode, and through the gonio-mirror of a three-mirror contact lens with the SL SCAN-1 in posterior mode. Results OCT scans could be obtained with the SL SCAN-1 of the peripheral retina through both, a common handheld lens and a three-mirror contact lens. The scans obtained through a three-mirror contact lens were of better quality, visualizing details of the different layers of the retina more clearly. The scans of the anterior chamber, obtained through the gonio-mirror of a three-mirror contact lens, visualized the open anterior chamber angle, with details of fine structures.Conclusions The SL SCAN-1 is a unique FD OCT system, which is able to scan not only the posterior pole and anterior segment but also the anterior chamber angle and the more peripheral retina. These four modalities combined into one device could make the SL SCAN-1 a very powerful aid in daily practice.

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Imaging the Ocular Anterior Segment With Real-Time, Full-Range Fourier-Domain Optical Coherence Tomography

Cited by 92 publications

References 39 publications

Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment

Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment

Anterior segment imaging with Spectral OCT system using a high-speed CMOS camera

Scanning beyond the limits of standard OCT with a Fourier domain optical coherence tomography integrated into a slit lamp: the SL SCAN-1

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