Immediate Dental Implants Enriched with L-PRF in the Esthetic Zone

Sehgal, Manoti; Puri, Lovleen; Yadav, Sapna; Malhotra, Puja; Phukela, Sumit Singh; Yadav, Bhupender; Raina, Bharti

doi:10.1155/2018/9867402

Cited by 9 publications

(10 citation statements)

References 13 publications

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“…Furthermore, the continued release of growth factors associated with L-PRF components, along with its densely polymerized structure, may have had a crucial role in hastening bone formation around the implant. 22,23 The use of L-PRF for gap management in immediate implant placement has been presented in several case reports [44][45][46][47][48] and clinical studies, [39][40][41][49][50][51] frequently in association with bone grafting materials. 52 However, only a handful of pre-clinical studies evaluating histologically the effect of L-PRF in this particular scenario have been reported in previous literature.…”

Section: Discussionmentioning

confidence: 99%

Effect of leukocyte‐platelet‐rich fibrin in bone healing around dental implants placed in conventional and wide osteotomy sites: A pre‐clinical study

et al. 2022

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Leukocyte‐platelet‐rich fibrin (L‐PRF) has been suggested for gap management for immediate implant placement when the distance is greater than 2 mm. However, there remains a paucity in hierarchically designed research to support this application. The present study aimed to evaluate the effect of L‐PRF on the osseointegration parameters of dental implants placed after conventional osteotomy of surgically created bone defects that simulate post extraction sockets in a canine model after 3, 6, and 12 weeks in vivo. Eighty dental implants (Intra‐Lock, Boca Raton, FL) were placed in the radius of 13 beagle dogs. The experiment consisted of 4 groups (n = 20 implants/group): 1) Regular osteotomy (Reg n/L‐PRF); 2) Regular osteotomy and implant placement with L‐PRF membrane (Reg L‐PRF); 3) Wide osteotomy with no gap management performed, where an osteotomy/bony defect (6 mm of diameter and ~5 mm deep) was created to simulate immediate implant placement in post‐extraction sockets, and the gap was left for spontaneous healing (Wide nL‐PRF); and 4) Wide osteotomy with L‐PRF gap management (Wide L‐PRF). L‐PRF membranes were obtained by blood drawn from each subject and centrifuged at 2700 rpm (408 RCF‐clot) for 12 min. In the experimental groups where L‐PRF was utilized, the membrane was inserted into the osteotomy site prior to implant placement. Six dogs had implants placed in the radius for 3 weeks; and 7 dogs had implants placed in the left radius for 6 weeks and in the right radius for 12 weeks. At the corresponding experimental time points, samples were harvested, and subjected to histological processing for qualitative and quantitative analyses, via bone‐to‐implant contact (BIC) and bone‐area‐fraction occupancy (BAFO). Qualitative analysis demonstrated increased amounts of bone formation around the implant and within the healing chambers over time for all groups. While comparable histological features were observed for both Reg groups (L‐PRF and nL‐PRF), the gap management performed in Wide L‐PRF group resulted in effective gap filling with improved bone growth in close proximity to the implant surface. Quantitative analyses of BIC and BAFO yielded higher values for both variables at 3 weeks for Wide L‐PRF (~38% and ~56% respectively) compared to Wide nL‐PRF (~20% for BIC and BAFO) (p < .03). No statistical differences were detected between Wide groups at 6 and 12 weeks, neither between Reg groups, independent of the association with or without the L‐PRF membrane at all healing times. L‐PRF placed within wide osteotomies, prior to implant placement, resulted in increased early bone formation compared to unfilled wide osteotomies at the early healing time (3 weeks in vivo).

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Section: Discussionmentioning

confidence: 99%

Effect of leukocyte‐platelet‐rich fibrin in bone healing around dental implants placed in conventional and wide osteotomy sites: A pre‐clinical study

et al. 2022

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“…Implant stability and periimplant tissue health decrease during the first weeks of healing due to changes occurring in bone and soft tissue, which cause aesthetic and biological concerns. Thus, it is necessary to establish a treatment protocol that provides the maintenance and preservation of periimplant tissues, with the focus on the installation of immediate loading implants (SEHGAL et al, 2018).…”

Section: Resultsmentioning

confidence: 99%

Immediate implant with immediate loading in the anterior region using L-PRF to preserve gingival aesthetic profile

Júnior¹,

Neto²

2019

IJAERS

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One of the challenges of the immediate immediately loaded implantation technique in aesthetic areas is the preservation of aesthetic support structures such as marginal ridges and soft tissues. In order to preserve the peri-implant structures and maintain the aesthetic volume of the alveolar process and thus the emergence profile of the implant prosthesis. Bone grafts, connective tissue grafts and use of biological membranes can be employed to cover the surgical bed to protect and preserve the volume of the socket, maintaining the prosthetic aesthetic profile safely and predictablyThis paper aims to present a clinical case of a patient with tooth root fracture 21. Atraumatic tooth extraction was performed with immediate implant installation. For the preservation of the peri-implant structures and maintenance of the gingival aesthetic profile, a bone graft was performed, with i-PRF agglutinated xenograft, collagen membrane and covering the gap, the L-PRF membrane and immediately loaded using a plastic ucla abutment and a tooth. made with an additional silicone wall. The case was evaluated at 7 days and 30 days and immediately afterwards the definitive prosthesis was performed and 90-day follow up was performed. Based on the initial results obtained, it can be concluded that the treatment had benefits providing a favorable prognosis with longer implant survival at the end of the osteointegration period.

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“…This growth factor because of the nature of fibrin keeps doing its activity for a longer period of time and promotes faster tissue regeneration. 12,13 PRF has the property of increasing tissue cicatrization during neovascularization, leading to faster tissue remodeling without any complications of the wound healing like pain and pus formation. In dentistry PRF is widely used in the treatment of gingivitis, periodontal defects, oral lesions, and palatal wound closure.…”

Section: Discussionmentioning

confidence: 99%

Prosthodontic Management of Single Anterior Missing Tooth with Immediate Loading Implant Using Leukocyte-Platelet-Rich Fibrin

Wahengbam¹,

Kalra²,

Kumar³

et al. 2021

Dental Journal of Advance Studies

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Immediate loading of dental implant in the anterior tooth region has been a growing trend and eliminates the compromised esthetics, function, discomfort, and inconvenience associated with traditional two-stage implant procedures. This case report presents the clinical application of implant placement with immediate loading using leukocyte-platelet-rich fibrin (L-PRF) in the anterior esthetic region. The implant was planned to rehabilitate in the anterior missing tooth region. As per the patient's desire, the implant was immediately loaded and L-PRF membrane was placed around the implant under local anesthesia on the day of surgery. The use of L-PRF for the maintenance of crestal bone and soft tissue at the implant sites provided an adequate clinical condition for better esthetics.

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Immediate Dental Implants Enriched with L-PRF in the Esthetic Zone

Cited by 9 publications

References 13 publications

Effect of leukocyte‐platelet‐rich fibrin in bone healing around dental implants placed in conventional and wide osteotomy sites: A pre‐clinical study

Effect of leukocyte‐platelet‐rich fibrin in bone healing around dental implants placed in conventional and wide osteotomy sites: A pre‐clinical study

Immediate implant with immediate loading in the anterior region using L-PRF to preserve gingival aesthetic profile

Prosthodontic Management of Single Anterior Missing Tooth with Immediate Loading Implant Using Leukocyte-Platelet-Rich Fibrin

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