“…The authors who have analyzed soft tissue changes associated with RME and SARME were more interested with naso-maxillary region ( 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ). They reported modifications in cheek, upper lip and nasal morphology which were explained majorly by the transversal enlargement of the maxilla, except for few studies ( 19 , 23 ) reporting that RME did not have significant clinical effects on the nose. Furthermore, it has been pointed out that the immediate maxillary advancement with downward and backward mandibular rotation during maxillary expansion could have an effect on the patients’ soft tissue profiles ( 24 , 25 , 26 , 27 , 28 , 29 , 30 ).…”