Immune Cells Activity, Nitrite Scanvenging and ABTS Radical Scavenging Activities of Codonopsis lanceolata Ethanol Extracts from Districts in Korea

Boo, Hee-Ock; Park, Jeong‐Hun; Kim, Hong Gi; Kim, Hag-Hyun; Kwon, Soo-Jeong; Seo, Dong-Yeon; Lee, Moon-Soon

doi:10.7732/kjpr.2016.29.3.289

Cited by 2 publications

(2 citation statements)

References 15 publications

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“…In another study, antioxidant potential of M. charantia samples obtained from different regions was determined by using DPPH, ABTS and Nitrite scavenging tests. As a result of the study, it was reported that the plant sample had significant antioxidant activity [25]. In a study conducted in Turkey, it was reported that the plant has a significant antioxidant effect on rats [26].…”

Section: Antioxidant Activitymentioning

confidence: 99%

Functıonal food Momordıca charantıa: bıologıcal actıvıtıes

Mohammed¹,

Uysal²,

Sevindik³

2023

Prosp. Pharm. Sc.

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Complementary medicine history includes a lot of knowledge based on human history. In this context, different plant species are used in the treatment and prevention of diseases. Plants are important natural productsthat attract attention with their nutritive and non-nutritive compounds. They contain many bioactive compounds that are not particularly nutritious but very important from a medical point of view. In our study, the biological activities of Momordica charantia reported in the literature were compiled. In addition, mineral, nutrient and chemical contents reported in the literature were compiled. The fruits of M. charantia are known as bitter gourd. In different parts of the world, it is used for many purposes as salad, direct food product, dried and spiced. It is used locally for different purposes in different countries. It is used as a supplement or sweetener in many foods, especially in East Asian countries. In our study, in addition to the nutritional properties of the plant, its medicinal properties were emphasized. As a result of the research, it was determined that the plant has many biological activities such as antioxidant, antimicrobial, antiinflammatory, antihyperglycemic, antiulcer, DNA protective, cytotoxic, anthelmintic, antiepimastigote, antiviral, immunomodulative, radioprotective, hepatoprotective, antidiabetes, antitumor, antiproliferative, antistress, hypoglycaemic, antimutagenic, or antiaging. In addition, it stands out with its nutritional properties. It is thought that it may be a natural source for the compounds reported in the literature data. Based on these studies, it is thought that Momordica charantia may be an important natural agent.

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Section: Antioxidant Activitymentioning

confidence: 99%

Functıonal food Momordıca charantıa: bıologıcal actıvıtıes

Mohammed¹,

Uysal²,

Sevindik³

2023

Prosp. Pharm. Sc.

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“…The species is known to exert various pharmacological effects in humans. The roots of C. lanceolata mainly contain triterpenoid saponins, including codonolasides I-V and lancemaside A-G (Boo et al, 2016;Moon et al, 2018). The saponins exhibit anti-inflammatory effects for conditions such as bronchitis and cough, insomnia, and hypomnesia.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Cytotoxicity on Human Cancer Cells and Antioxidant and Immune Cell Activities of Codonopsis lanceolata Root Extracts Stored at Different Temperatures and for Different Durations

Boo¹,

Shin²,

Kim³

et al. 2019

HST

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Codonopsis lanceolata is widely consumed in South Korea; however, its medicinal applications have not been explored in detail. The present study aimed to evaluate the xanthine oxidase (XO) inhibitory activity, reducing power, immune activity, and cytotoxicity of 30% ethanolic extracts of C. lanceolata roots stored at different temperatures (5, 15, 25, 35, and 45°C) and for different storage periods (0, 15, 30, 45, 60, 75, and 90 days). The growth of human T and B cells increased when treated with the root extracts stored at low temperatures for a short period, in a concentration-dependent manner. The XO inhibitory activity of the C. lanceolata roots stored at 5°C and 15°C was higher than for those stored at 45°C. The XO inhibitory activity of the C. lanceolata roots gradually deceased with increasing storage period. The reducing power of the extracts increased significantly in a concentration-dependent manner. Reducing power of the root storage temperature for all temperatures and storage periods using 5 mg·mL -1 extract was higher than that for the other extract concentrations. Cytotoxic activity of C. lanceolata roots on human cancer cell lines (e.g., HeLa, Calu-6, and MCF-7) decreased as storage temperatures decreased from 45°C to 5°C. The cytotoxic effect on the MCF-7 cell line was relatively higher than that on the HeLa and Calu-6 cell lines. The results suggest that the root extract of C. lanceolata can be used to modulate immune response and is also a natural food additive with excellent physiological functionality.

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Immune Cells Activity, Nitrite Scanvenging and ABTS Radical Scavenging Activities of Codonopsis lanceolata Ethanol Extracts from Districts in Korea

Cited by 2 publications

References 15 publications

Functıonal food Momordıca charantıa: bıologıcal actıvıtıes

Functıonal food Momordıca charantıa: bıologıcal actıvıtıes

Evaluation of Cytotoxicity on Human Cancer Cells and Antioxidant and Immune Cell Activities of Codonopsis lanceolata Root Extracts Stored at Different Temperatures and for Different Durations

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