Immune Complexes-Like Disease in the Course of Enterobacter cloacae sepsis Due to Cholelithic Cholecystitis, Preceded by Influenza Vaccination

Abstract

The authors present a case of a male who, a week after influenza vaccination presented with abdominal symptoms-pain in the right epigastrium followed by pyrexia, muscle pain, disturbed liver and kidneys function as well as consciousness disorders. Immune complex-like disease and Enterobacter cloacae sepsis due to cholelithic cholecystitis were diagnosed. In this case, the suspected correlation between vaccination and immune complex-like disease resulted mainly from two reasons-the onset of symptoms after few days after vaccinations and clinical improvement after plasmaferesis. In etiopathogenesis of this specific case the similar immunogenicity of vaccine compounds and Enterobacter cloacae antigens, and patient genetic predisposition should be considerated.