Immune Hemolytic Anemias

Successful Treatment with Ascorbic Acid in a Case of Methemoglobinemia Due to Glucose-6-Phosphate Dehydrogenase Deficiency

“…Nevertheless, in patients with G6PD deficiency, the enzyme cannot protect cells against oxidative stress that develops in red blood cells and leads to hemolysis due to certain drugs, metabolic conditions, and infections. 2 Additionally, G6PD enzyme deficiency has been reported to trigger methemoglobinemia by inhibiting the methemoglobin (MetHb) reductase enzyme. 3 Therefore, understanding the mechanisms and consequences of G6PD deficiency is crucial in the diagnosis and treatment of related conditions.…”