Immune relations between mother and foetus in the viviparous poeciliid fish Xiphophorus hellerii Haeckel

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Allografts within the ovary are rejected as rapidly as those made elsewhere; the Xiphophorus ovary is thus not a favoured site for allograft survival because of high gonadal hormone levels. Removal of one embryo of a brood from the ovary and its reimplantation elsewhere does not affect the development of the remaining members of the brood. Immune rejection of the foetus during gestation is not avoided by the absence of lymphatic drainage from the ovary.

Section: Discussionmentioning

confidence: 96%

“…It can be secn that after TABLE 111. Presence, in 2 embryos found within the ovarian lumen, of 11 histological characters (Hogarth, 1972) (1) Notochord…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Immune relations between mother and foetus in the viviparous poeciliid fish Xiphophorus hellerii Haeckel

Hogarth¹

1972

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“…Thus, it is important to understand how viviparous fishes have evolved in this context. A few early studies by Hogarth (, b, ) revealed that immunological rejection could occur in the ovary of a viviparous fish, green swordtail Xiphophorus helleri Heckel 1848.…”

Section: Introductionmentioning

confidence: 99%

Ovarian cavity fluid of the viviparous surfperch Neoditrema ransonnetii suppresses the spontaneous cytotoxic activity of head‐kidney leucocytes against xenogeneic targets

Yokozawa

Nakamura

Saito

et al. 2015

In this study, the effect of ovarian cavity fluid (OCF) from a surfperch Neoditrema ransonnetii on the cytotoxic activity of leucocytes was investigated. In an assay targeting RTG-2, a cell line derived from rainbow trout Oncorhynchus mykiss gonads, leucocytes from both the spleen and head kidney showed spontaneous killing activity. Pre-incubation with OCF significantly suppressed the cytotoxic activity of head-kidney leucocytes towards RTG-2. This suppressive activity was due to the presence of low molecular-mass materials. These results suggest that OCF plays significant roles in pregnancy by its ability to modulate cytotoxicity with maternal leucocytes.

“…The foetus of the viviparous teleost, Xiphoplzorus hellerii Haeckel is, during gestation, in a position analogous to that of a tissue allograft. The mother is immunologically competent (Hogarth, 1968) and the foetus antigenically mature (Hogarth, 1972a), while the site of gestation (the ovary) appears to lack any special properties which would make it a favourable site for allograft survival (Hogarth, 1972b).…”

Section: Introductionmentioning

confidence: 99%

Immune relations between mother and foetus in the viviparous poeciliid fish Xiphophorus hellerii Haeckel

Hogarth

1973

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Advanced embryos of the viviparous pocciliid fish Xiphophorus helleriz (swordtail) were removed from the site of gestation within the ovary and re-implanted into the peritoneal cavities of unrelated immunologically competent adults of the same species. Most of those transplanted with intact fertilization membranes were normal in appearance, and many were clearly still alive. Those transplanted without a fertilization membrane were all dead, with lymphocyte infiltration and other evidence of rejection as allograft$. The integrity of the membrane in late pregnancy was indicated by swelling of follicles in hypoosmotic liquid.It was concluded that thc fertilization membranc is capable of protecting an antigenically foreign embryo in an immunologically hostile environment, and that it probably serves this function during normal pregnancy.