Immune response to cold exposure: Role of γδ T cells and TLR2‐mediated inflammation
Daniel Vasek,
Peter Holicek,
Frantisek Galatik
et al.
Abstract:The mammalian body possesses remarkable adaptability to cold exposure, involving intricate adjustments in cellular metabolism, ultimately leading to thermogenesis. However, cold‐induced stress can impact immune response, primarily through noradrenaline‐mediated pathways. In our study, we utilized a rat model subjected to short‐term or long‐term mild cold exposure to investigate systemic immune response during the cold acclimation. To provide human relevance, we included a group of regular cold swimmers in our … Show more
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