Immuno-modulating effect of Astragalus polysaccharides on the immune reactions of peripheral blood lymphocytes in pigs

Li, J.F.; Guo, Kejun; Liu, F.H.; Zhang, N.W.; Liu, F.Q.; Xu, Jianqin

doi:10.1016/j.ejphar.2011.09.242

Cited by 2 publications

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“…The polysaccharide of L. barbarum is its major bioactive component and has been widely used as one of the main chemical components in a traditional Chinese medicine named Ningxia wolfberry. Astragalus polysaccharide has been reported to be a potential additive used in the vaccination of humans and animals so as to improve immune functions both in cellular and humoral immune responses ( 10 ). Astragalus polysaccharide was reported to enhance the antioxidant capacity while adding to the diet of goats ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Response of Growth Performance, Blood Biochemistry Indices, and Rumen Bacterial Diversity in Lambs to Diets Containing Supplemental Probiotics and Chinese Medicine Polysaccharides

et al. 2021

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This study aims to investigate the effects of probiotics and Chinese medicine polysaccharides (CMPs) on growth performance, blood indices, rumen fermentation, and bacteria composition in lambs. Forty female lambs were randomly divided into four groups as follows: control, probiotics, CMP, and compound (probiotics + CMP) groups. The results showed that probiotics treatment increased the concentrations of blood glucose (GLU) and immunoglobulin G (IgG) and enhanced rumen microbial protein contents but declined the value of pH in rumen fluid compared with the control (P < 0.05). Furthermore, supplementation with CMP enhanced the average daily gain (ADG) and the contents of IgA, IgG, and IgM in the serum but decreased the F:G ratio compared with the control (P < 0.05). Besides, both CMP and compound (probiotics + CMP) treatments decreased the ratio of acetic acid and propionic acid compared with the control (P < 0.05). High-throughput sequencing data showed that at the genus level, the relative abundance of Veillonellaceae_UCG-001 in the probiotics group was increased, the relative abundance of Succiniclasticum and norank_f__Muribaculaceae in the CMP group were enhanced, and the relative abundance of Ruminococcaceae_UCG-002 in the compound group was raised compared with the control (P < 0.05). In summary, supplementation with probiotics can promote rumen protein fermentation but decrease the diversity of bacteria in rumen fluid; however, CMP treatment increased the relative abundance of Fibrobacteria, changed rumen microbial fermentation mode, increased the immune function, and ultimately improved the growth performance.

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Section: Introductionmentioning

confidence: 99%

Response of Growth Performance, Blood Biochemistry Indices, and Rumen Bacterial Diversity in Lambs to Diets Containing Supplemental Probiotics and Chinese Medicine Polysaccharides

et al. 2021

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“…In another study, it was showed that APS in different dosages (5,10 and 20 mg kg) rapidly increased the Foot and Mouth Disease Virus specific antibody in a dose-dependent manner in fifteen four-week-old Yorkshire pigs. APS also significantly up-regulated the mRNA expression of the production of Th1 (IFN-γ) and Th2 (IL-6) cytokines in peripheral blood lymphocytes from the immunized pigs [31] .…”

Section: Research On Pigsmentioning

confidence: 95%

Recent Contributions to Development of Herbal-Based Immunomodulators for Farm Animals

Grigore¹

2017

JISB

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Safety and quality of food and feed today is at a high level, the challenge is to ensure a healthy daily diet but affordable for everyone. But the most important link for obtaining sanogen products for food is to use organic, eco-friendly and not polluted agricultural raw materials (vegetable and animal) and most of all, to "produce for man in harmony with nature".Use of immunostimulants is a unique approach for farm owners as they undertake methods of controlling disease losses in their facilities. Microbial diseases are limiting factors in all forms of intensive culture and a problem is that few approved chemotherapeutic agents are available for use in animal food because of growing concerns for consumers liability and for accumulation of substances in the environment. Many medicinal plants showing immunomodulatory activity have been used instead of drugs because of their low toxicity for the host system.This review aims at presenting recent contributions to development of herbal-based immunomodulators for farm animals, a total of 97 studies from 2000 -2016 concerning species of economic interest (various categories of fish -tilapia, trout, carp; shrimps; cattle; pigs and chickens). In veterinary practice, innovative eco-friendly products that could improve or prevent some disorders became of great actuality and therefore the research on animals of economic interest should continue for the benefit of both animals and humans.use organic, eco-friendly and not polluted agricultural raw materials (vegetable and animal) and most of all, to "produce for man in harmony with nature".In veterinary practice, reasons for producing a poor immunity to an infection can include: the infection itself -a number of infections suppress immunity and these particularly include some viruses and mycoplasma; stress -this comes in many different forms for an animal; nutrition -an inadequate overall diet may suppress immunity; deficiency in individual feed ingredients -especially proteins, vitamin A and E, selenium, etc.; the production status of the animal -immune response is often less in the mother close to birth; age of animal -very young or old are often imunosuppressed; other diseases -especially cancer, metabolic diseases (e.g. pregnancy toxemia in sheep, fatty liver in cattle); vaccination process -insufficient vaccine given, out-

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Immuno-modulating effect of Astragalus polysaccharides on the immune reactions of peripheral blood lymphocytes in pigs

Cited by 2 publications

References 0 publications

Response of Growth Performance, Blood Biochemistry Indices, and Rumen Bacterial Diversity in Lambs to Diets Containing Supplemental Probiotics and Chinese Medicine Polysaccharides

Response of Growth Performance, Blood Biochemistry Indices, and Rumen Bacterial Diversity in Lambs to Diets Containing Supplemental Probiotics and Chinese Medicine Polysaccharides

Recent Contributions to Development of Herbal-Based Immunomodulators for Farm Animals

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