Immunocontraception for Animals: Current Status and Future Perspective

Naz, Rajesh K.; Saver, Ashley E.

doi:10.1111/aji.12431

Cited by 34 publications

(35 citation statements)

References 114 publications

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“…; Jurdak et al . ; Naz & Saver ). It is therefore foreseeable that applications of current technology, let alone new technology, will reduce the cost of control, increase effectiveness and further reduce animal suffering if governments choose to invest in this area.…”

Section: Animal Welfare and The Ethics Of Aerial Cullingmentioning

confidence: 99%

“…Ongoing control is a very standard practice and is why the Australian Capital Territory has remained largely feral horse free (ACT Government 2007). The nature of pest species control is undergoing a technological revolution at the moment (Campbell et al 2015;Jurdak et al 2015;Naz & Saver 2016). It is therefore foreseeable that applications of current technology, let alone new technology, will reduce the cost of control, increase effectiveness and further reduce animal suffering if governments choose to invest in this area.…”

Section: Animal Welfare and The Ethics Of Aerial Cullingmentioning

confidence: 99%

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Impacts of feral horses in the Australian Alps and evidence‐based solutions

Driscoll¹,

Worboys

Allan³

et al. 2019

Eco Management Restoration

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Summary New evidence of impacts by feral horses in Australia's alpine parks systems confirms they endanger threatened species and extensively damage critically endangered bog communities that could take millennia to recover. These impacts are not confounded by effects of deer and accumulate over time, even when only a small number of feral horses (~100) are present. With protected areas representing only a small proportion of the area of the Australian states of New South Wales (9.3%) and Victoria (17%), allowing feral horses to degrade reserves is not a reasonable management compromise, is contrary to the purpose of the protected area system and conflicts with international obligations. Modelling and decades of management experience indicate that trapping alone does not control feral horse numbers. Trapping and fertility control can work in small populations, but not when there are several thousand horses in remote areas. Aerial culling is needed to cost‐effectively and humanely control feral horse populations. The relatively small amount of suffering feral horses experience during a cull is outweighed by (i) avoiding suffering and death of horses from starvation and thirst, (ii) avoiding the suffering of native animals displaced by horses and (iii) avoiding the ethical concerns of driving threatened species towards extinction. Objections to aerial culling on welfare and cultural grounds are contradicted by evidence. Improving knowledge in the general community about what is at stake is long overdue because without this knowledge, small groups with vested interests and unfounded claims have been able to dominate debate and dictate management actions. As a result of ineffective management, horse populations are now expanding and causing well‐documented damage to Australia's alpine parks, placing at risk almost $10M spent on restoration after livestock grazing ended. The costs of horse control and restoration escalate the longer large horse populations remain in the alpine parks. It is crucial that feral horse numbers are rapidly reduced to levels where ecosystems begin to recover. Aerial culling is needed as part of the toolbox to achieve that reduction.

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Section: Animal Welfare and The Ethics Of Aerial Cullingmentioning

confidence: 99%

Section: Animal Welfare and The Ethics Of Aerial Cullingmentioning

confidence: 99%

Impacts of feral horses in the Australian Alps and evidence‐based solutions

Driscoll¹,

Worboys

Allan³

et al. 2019

Eco Management Restoration

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“…Immunocastration or vaccination against the GnRH‐I hormone produces an immunological barrier between the hypothalamus and the anterior hypophysis, modifying gonadal function and sexual behavior . This is a promising alternative to reproductive control and has been investigated in domestic, productive, and wild animals . Given the low immunogenicity of this hormone, it becomes necessary to increase the antigenic immune response using adjuvants …”

Section: Introductionmentioning

confidence: 99%

The immune profile induced is crucial to determine the effects of immunocastration over gonadal function, fertility, and GnRH‐I expression

Siel

Loaiza

Vidal

et al. 2017

American J Rep Immunol

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“…Furthermore, the sources of native CRISP1 protein limit its further application. Recombinant CRISP1 is relatively easy to obtain and had successfully produced a specific immune response, but it needs to be used in conjunction with the Freund's adjuvants, which are primarily related to the injection site reactions . As the first study on DNA vaccination based upon sperm antigens YLP12 and FA‐1 by Naz RK et al which showed exciting immunocontraceptive effects, several other sperm antigen‐based DNA vaccines have been investigated .…”

Section: Discussionmentioning

confidence: 99%