2023
DOI: 10.36233/0372-9311-113
|View full text |Cite
|
Sign up to set email alerts
|

Immunogenesis in Lassa fever and prospects for vaccine development

Abstract: Analysis of literature data on the structure of the Lassa virus genome and its strain diversity has shown that the molecular heterogeneity of strains is essential in the design of vaccines and evaluation of their efficacy, which is determined by the relevant WHO recommendations. During virus reproduction, Lassa counteracts cellular immunogenesis by suppressing the expression of the suppressor of signaling proteins, cytokines and the RLR receptor that recognizes viral two-segmented RNA. The GP protein, wh… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Publication Types

Select...

Relationship

0
0

Authors

Journals

citations
Cited by 0 publications
references
References 58 publications
0
0
0
Order By: Relevance

No citations

Set email alert for when this publication receives citations?