Immunoglobulins in Teleost

Mendoza, Manuel; Magadán, Susana

doi:10.1007/978-3-030-85420-1_7

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Adaptive Immunity1

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2023

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“…To date, no B cells have been identified that jointly express IgT and IgM, indicating a separate development and lineage for each isotype [18]. The hypothesis of separate lineages is further supported by the lack of evidence demonstrating classswitching capabilities of Igs in teleost fish [37]. The results from these studies are only possible because monoclonal antibodies (mAbs) have been developed that are specific to various Ig forms in teleosts.…”

Section: Adaptive Immunitymentioning

confidence: 99%

An Introduction to Relevant Immunology Principles with Respect to Oral Vaccines in Aquaculture

Jones,

Cain

2023

Microorganisms

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Vaccines continue to play an enormous role in the progression of aquaculture industries worldwide. Though preventable diseases cause massive economic losses, injection-based vaccine delivery is cost-prohibitive or otherwise impractical for many producers. Most oral vaccines, which are much cheaper to administer, do not provide adequate protection relative to traditional injection or even immersion formulas. Research has focused on determining why there appears to be a lack of protection afforded by oral vaccines. Here, we review the basic immunological principles associated with oral vaccination before discussing the recent progress and current status of oral vaccine research. This knowledge is critical for the development and advancement of efficacious oral vaccines for the aquaculture industry.

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Section: Adaptive Immunitymentioning

confidence: 99%