Immunological response in mice immunised via oral route with açaí (<i>Euterpe oleracea</i>Mart.)

Oliveira, Marília Porto; Marques, Márcia Maria Mendes; Maia, Fábio Erlan Feitosa; Pereira, Camila Pinheiro; Silva, Bruno Bezerra da; Almeida, Lia Magalhães de; Castro, Luana Mara Silva de; Maia, Carla Soraya Costa; Guedes, Maria Izabel Florindo

doi:10.1080/09540105.2013.864606

Cited by 4 publications

(3 citation statements)

References 22 publications

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“…Analyzing IgE and IgG1, positive results were observed in the western blotting test showing that LP used was not able to generate the production of immunoglobulins. This result is relevant because allergic reactions from foods are characterized by specific IgE and IgG1 levels in serum and by activating gut mast cells (Guedes & Pereira, 2005;Oliveira et al, 2013). The western blotting test of the sample used in the present study is not similar to the results reported by Sandeep, Alok, Amita, Anurag, and Bhushan (2011) who evaluated the allergenic responses of BALB/c mice immunized with red kidney beans (P. vulgaris cv.…”

Section: Discussioncontrasting

confidence: 53%

Humoral immune response in mice immunized by oral route with phaseolamine extracted from common bean (Phaseolus vulgaris)

Silva

Gama

Oliveira

et al. 2017

Food and Agricultural Immunology

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The prevalence of obesity is increasing in Brazil, generating high costs for the health system. In the search for alternative therapies to control the obesity, several researches seek active compounds in natural products in order to find better pharmacological effects. Inhibitors of α-amylase such as phaseolamine extracted from common beans (Phaseolus vulgaris) have shown satisfactory results in weight loss. The present study aimed to verify the possibility of phaseolamine-causing allergic reactions through the humoral response in mice sensitized with phaseolamine. Swiss female mice (n = 10) were sensitized orally with 100 µg of lyophilized phaseolamine diluted in water for 10 consecutive days and reinforced on the 21th and 35th days after the beginning of this experiment. The production of immunoglobulins IgG, IgG1 and IgE was measured by ELISA and western blotting. The immunological response was investigated and it was found that phaseolamine induced the synthesis of IgG and did not induce the synthesis of IgG1 and IgE. The present study indicates that the product did not cause allergic reactions.

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Section: Discussioncontrasting

confidence: 53%

Humoral immune response in mice immunized by oral route with phaseolamine extracted from common bean (Phaseolus vulgaris)

Silva

Gama

Oliveira

et al. 2017

Food and Agricultural Immunology

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“…This food was introduced to the Northeast region and its consumption has increased over the past 10 years. Recent research has suggested its insertion into the group of food allergens [ 26 ]. Among the aforementioned fruits, bananas and avocados are classically related to cross allergy with latex [ 13 ], while there are reports in the literature of contact dermatitis with guava [ 27 ], although with no solid references to food allergy.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of reported food allergies in Brazilian preschoolers living in a small Brazilian city

Correia

Antunes

Taborda-Barata

et al. 2022

Allergy Asthma Clin Immunol

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Introduction Although the prevalence of allergic diseases, including food allergies, has increased over recent decades, relevant information on this topic is still lacking, particularly in younger children living in small cities. Objective To investigate the prevalence of reported food allergies in preschoolers in Limoeiro/Pernambuco, Brazil. Methods This was a cross-sectional study with preschoolers. Parents/guardians of all preschoolers enrolled at municipal schools between March and June 2019 (total of 619) were invited to complete a screening questionnaire (total of 619). Another 151 questionnaires were applied on the streets of the town. For positive responses, a second, more detailed and validated questionnaire was completed. Results A total of 412 questionnaires were returned, of which, 47 presented a positive response to food allergies and only 29 (7.04%) identified a particular food. The most frequently reported food items were shrimp, mollusks, pork, fruit and milk. Of the 29 who identified foods, 22 responded to the detailed questionnaire, resulting in only 4 (0.97%) positive responses. Of these, two were later discarded through clinical examinations and an open oral provocation test, resulting in a final prevalence of 0.48% of confirmed food allergies. Conclusion The prevalence of reported food allergies was lower than that described in previous studies. The most commonly mentioned foods were shrimp, mollusks and pork, with more reports of multiple food allergies, even in children who had never been previously exposed to these possible allergens, which highlights the relevance of perception in reported food allergy studies.

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“…According to Pereira and Guedes (2005) and Oliveira et al (2013), the allergic reactions from foods are characterized by specific IgE and IgG1 levels in serum and by activating gut mast cells.…”

Section: Discussionmentioning

confidence: 99%

Humoral immune response in mice immunized orally with conventional and transgenic soy extracts ( Glycine max )

Holanda

Fiorio

Silva

et al. 2019

Food and Agricultural Immunology

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The soybean is widely used in food industry due to its nutritional and functional qualities, but some studies have pointed it as a potent food allergen, especially in children. The concentration of IgG, IgG1 and IgE immunoglobulins in mice supplemented orally with common and transgenic soy was analysed. Mice were divided into two groups (6 animals each): lyophilized conventional soy (LCS) and lyophilized transgenic soy (LTS). Both received 100 μg of extracts for 10 consecutive days. Animals before immunization (pre-immune) formed the control group. The serum samples of the animals were undergone enzyme-linked immunosorbent assay (ELISA). The results of the ELISA tests showed that LCS and LTS induced the synthesis of specific IgG1 and IgG classes immunoglobulins and induced the formation of IgE immunoglobulin when evaluated by western blotting test. These results evidence the allergenicity of soybean and individuals with some food hypersensibility should avoid the consumption of this food.

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Immunological response in mice immunised via oral route with açaí (Euterpe oleraceaMart.)

Cited by 4 publications

References 22 publications

Humoral immune response in mice immunized by oral route with phaseolamine extracted from common bean (Phaseolus vulgaris)

Humoral immune response in mice immunized by oral route with phaseolamine extracted from common bean (Phaseolus vulgaris)

Prevalence of reported food allergies in Brazilian preschoolers living in a small Brazilian city

Humoral immune response in mice immunized orally with conventional and transgenic soy extracts ( Glycine max )

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