Impact of a Single Intracoronary Administration of Adiponectin on Myocardial Ischemia/Reperfusion Injury in Pig Model

Shibata, Rei; Kondo, Kazuhisa; Ouchi, Noriyuki; Walsh, Kenneth; Murohara, Toyoaki

doi:10.1016/j.cardfail.2009.07.166

Cited by 1 publication

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“…(9,10) One possible reason behind this is thought due to cardio protective substances like adiponectin, leptin, and resistin released by adipose tissue. (11)(12)(13)(14)(15)(16)(17) Through extensive research, improvement and suggestions have been proposed, the east Indian population is not yet studied for the immediate in-hospital mortality post ACS patients according to their level of body fat percentage. Apart from the geographical location, the population differs in dietary, social, behavioral and other genetically determined parameters .…”

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confidence: 99%

Immediate outcomes of Acute Coronary Syndrome: A hospital-based prospective observational study in a tertiary care institute in West Bengal, India

Sarkar¹

2019

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Introduction: Death due to Cardiovascular morbidities is one of the biggest health burden in India as well as worldwide. It is important to know the factors that may influence the outcome of the patients with Acute Coronary Syndromes (ACS). Methods: A total of 112 patients with diagnosed ACS admitted at the Department of Cardiology in a tertiary care institute in West Bengal, India were monitored from the time of admission to the discharge or outcome. They were measured for several anthropometric parameters like height, weight, body fat percentage, BMI, waist circumference etc. and various other biochemical and cardiovascular tests were done, and they were noted for the outcome in terms of recovery following discharge or death, for a maximum of 10 days post-ACS. The data were analyzed by SPSS 20 and Kaplan-Meier survival analysis was done. Results: Most common ACS was found to be left anterior descending artery ST segment elevated myocardial infarction (STEMI) (68.7%). Mortality observed during the 10-day observation period was 16.1%. Mortality rate did not vary significantly with the type of ACS (p = .899). Survival Analysis showed that there were significantly more chances of survival in the patients with percutaneous coronary intervention (PCI) in comparison with the patients who received only thrombolysis in the beginning of the time (p = .019) and at the end of the observation period (p = .037). The survival curves for patients based on BMI, waist circumference and body fat percentage did not vary significantly (p >.05). Conclusion:It could be concluded from the present study that survival after ACS significantly associated with PCI and not with obesity or overweight.

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Section: Introductionmentioning

confidence: 99%

Immediate outcomes of Acute Coronary Syndrome: A hospital-based prospective observational study in a tertiary care institute in West Bengal, India

Sarkar¹

2019

jmscr

View full text Add to dashboard Cite

show abstract

Impact of a Single Intracoronary Administration of Adiponectin on Myocardial Ischemia/Reperfusion Injury in Pig Model

Cited by 1 publication

References 37 publications

Immediate outcomes of Acute Coronary Syndrome: A hospital-based prospective observational study in a tertiary care institute in West Bengal, India

Immediate outcomes of Acute Coronary Syndrome: A hospital-based prospective observational study in a tertiary care institute in West Bengal, India

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