Impact of an Antimicrobial Stewardship Intervention on Shortening the Duration of Therapy for Community-Acquired Pneumonia

Abstract

The duration of therapy for CAP was excessive at our institution and was decreased with a stewardship intervention. Confirmatory studies at other institutions are needed; efforts to assess and reduce duration of therapy for CAP should be strongly considered.

Characteristics of Antimicrobial Stewardship Programs at Veterans Affairs Hospitals: Results of a Nationwide Survey

“…18 Little evidence is available about how ASP structures and processes relate to effective AS, and there is a lack of specificity of these structures and processes given the wide range of implementation strategies. The science guiding AS is largely based on uncoordinated, single-site trials that focus on process measures, [19][20][21][22][23][24][25] leaving gaps in evidence that would identify highly effective components and processes for implementation. For example, audit and feedback have often been cited as an effective strategy, 26 yet their targets and implementation strategies remain unclear.…”

Comparative analysis of the management of patients with community-acquired pneumonia in the Republic of Tatarstan: the experience of the first decade of the XXI century

“…Вероятно, это и позволило удержать значения смерт ности на одном уровне в 2000 и 2010 гг., несмотря на то, что этиология пневмоний менялась и грипп вно сил свои коррективы в эпидемиологические показа тели, как это было в 2009 г., в т. ч. в РТ [8]. Значи мость разработки и контролируемого внедрения стандартов и рекомендаций по ведению больных ВП была подтверждена исследованиями, проведенными в США [9], Великобритании [10] и других странах.…”

Antibiotic use in Departments of Internal Medicine of Lazio

“…Specifically, 7 and 10 days of treatment for inpatients with community acquired pneumonia were equally effective in terms of clinical outcome, length of stay and 30-day readmission rates. 19,20 Similarly, for patients with ventilator associated pneumonia, 8-10 days of treatment have been proposed in substitution of the usual two weeks course [21][22][23] and the same proposal has been made for patients with cellulitis, pyelonephritis and intra-abdominal infection. [24][25][26][27][28] Moreover, IDSA/SHEA guidelines suggest using inflammatory biomarker as PCT to shorten antimicrobial exposure, especially in intensive care units.…”