Impact of endothelial dysfunction on gender-specific vascular and neurocognitive heterogeneity in multifocal atherosclerosis in elderly patients

The worlds older population is growing dramatically. At the same time, ensuring an appropriate high standard of living for the elderly by reducing of morbidity and disability of geriatric patients is one of the main objectives of the modern healthcare system. However, changes associated with body aging necessitate application of novel approaches to the correction of pharmacotherapy and usage of specialized dosage forms. Such medicinal products provide both an appropriate therapeutic effect and facilitate their use. Presented review considers several features of pharmacotherapy of geriatric patients.

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Problems associated with effective pharmacotherapy of the elderly patients (geriatrics): A review

Korol

Егорова

Kudlаy

et al. 2022

Terapevticheskii arkhiv

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Modern extemporaneous formulations in the geriatric care management: current opportunities and future challenges. A review

Korol

Егорова

Kudlаy

et al. 2022

Terapevticheskii arkhiv

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Age-associated disorders, including cognitive functions, that often occur in geriatric patients, necessitate the use of novel approaches to provide appropriate medical care, pharmacoprophylaxis and pharmacotherapy among them. At the same time, an important objective of the national healthcare system is not only stimulating of pharmaceutical companies and pharmacies to expand the range of medicines intended for elderly patients, but also increasing availability of medicinal products, including the integration of extemporaneous formulations into clinical practice. Presented review considers several features of the regulation of the use of extemporaneous formulations in the treatment of geriatric patients. Examples of prescriptions that are used in Russian medical practice and are of the greatest interest in the treatment of elderly patients are also presented.

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Stenotic remodeling of coronary vessels in the elderly patients with high cardiovascular risk and the presence of multifocal atherosclerosis

et al. 2021

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Aim. Identifying persons who are distinguished by an increased frequency of stenosing atherosclerosis of the coronary arteries also affects the process of identifying the features of the analyzed disease. Material and methods. The main research method was the method of hierarchical analysis of categorical variables. At the same time, they differentiated into 3 clusters depending on the age and duration of the disease. The age of the analyzed patients is from 61 to 75 years. For diagnostics, a general assessment of the clinical condition, coronary angiography, and echodopleroscopy of a number of carotid and lower limb arteries were performed. The research base is the Regional Vascular Center of Ufa. Results. The work revealed that the age-related feature of 65+ is a stable lesion of the coronary vessels. At the same time, it was determined that both men and women suffer from this. Conclusion. It has been shown that this is characterized by an increased frequency of stenosing-type remodeling.

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Impact of endothelial dysfunction on gender-specific vascular and neurocognitive heterogeneity in multifocal atherosclerosis in elderly patients

Cited by 5 publications

References 15 publications

Problems associated with effective pharmacotherapy of the elderly patients (geriatrics): A review

Problems associated with effective pharmacotherapy of the elderly patients (geriatrics): A review

Modern extemporaneous formulations in the geriatric care management: current opportunities and future challenges. A review

Stenotic remodeling of coronary vessels in the elderly patients with high cardiovascular risk and the presence of multifocal atherosclerosis

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