Impact of fibronectin on surface properties of intraocular lenses

Abstract

This study associates IOL materials, surface modifications, and the role of FN preadsorption with SCA values reflecting surface hydrophobicity versus hydrophilicity. It provides a rationale for specific IOL selection as a function of the clinical setting, and a basis for IOL development using tailored surface physicochemistry to enhance biocompatibility and to reduce susceptibility to implant infection.

Surface roughness of intraocular lenses with different dioptric powers assessed by atomic force microscopy

“…Various testing procedures have been applied to determine the chemicophysical characteristics of optic surfaces, including contact angle measurements, [13][14][15][16] dynamic mechanical measurements, 17 scanning electron microscopy (SEM), [18][19][20][21][22] in vitro assays, 23,24 and atomic force microscopy (AFM). 25,26 The contact angle-measurement method generates valuable information about the material surface and the potential biomaterial interactions.…”