Impact of home confinement during COVID-19 pandemic on Parkinson's disease

Kumar, Niraj; Gupta, Ravi; Kumar, Hrishikesh; Mehta, Sahil; Rajan, Roopa; Kumar, Deva; Kandadai, Rukmini Mridula; Desai, Soaham; Wadia, Pettarusp M; Basu, Purba; Mondal, Banashree; Sanchita, .; Rawat, Ankita; Meka, Sai Srilakshmi; Mishal, Bhushan; Prashanth, L.K.; Srivastava, Achal Kumar; Goyal, Vinay

doi:10.1016/j.parkreldis.2020.09.003

Cited by 36 publications

(35 citation statements)

References 6 publications

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“…Access to this large dataset enabled a stratification based on gender and/or geographic location, complementing existing studies and offering a unique insight into the susceptibility or resilience of different sub-populations of PD patients to the COVID-19 confinement. Approximately half of the participants noted changes in motor and non-motor symptoms, in accordance with previous studies reporting an aggravation of behavioral and psychological symptoms, a worsening of sleep disorders, depression and anxiety as well as reduced physical activity of patients with PD as a result of confinement or loneliness [ [5] , [6] , [7] , [26] , [27] , [28] , [29] , [30] , [31] , [32] ]. Patients also reported increased anxiety and worsened cognitive abilities (30.9 % and 17.9 % positive responses, respectively) during confinement, without significant differences between gender and living environment.…”

Section: Discussionsupporting

confidence: 88%

“…These observations indicate that geographical location, such as Alberta vs. Québec in our study, along with different sociocultural backgrounds could affect a patient’s perceived risk to contract the virus. Lastly, a recent study assessed the association between worsening of motor or non-motor features during the COVID-19 pandemic and four variables related to lifestyle or medical support namely (1) “available home support during lockdown”, (2) “duration of home confinement”, (3) “duration of Parkinson’s disease” and (4) “difficulty seeking formal neurologist’s opinion and/or medicines for Parkinson’s disease” [ 28 ]. It was found that some – but not all – clinical features are affected by these variables, emphasizing that clinical manifestations of PD are complex and can be influenced by more than one external factor.…”

Section: Discussionmentioning

confidence: 99%

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Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience

Jacquet¹,

Bogard²,

Normandeau³

et al. 2021

Parkinsonism & Related Disorders

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Background The COVID-19 pandemic has necessitated the social isolation of the population and the rapid implementation of remote care for patients with neurodegenerative diseases. The objective of this study was to explore the perceived impact of confinement in patients with Parkinson’s disease and document the effects of gender and living environment. Methods We recruited two cohorts from the Canadian provinces of Québec and Alberta, which differed in the dynamics of COVID-19 spreading at the time of the study, and administered a questionnaire on the perceived effects of confinement on daily living and disease management. Results The data reveals that approximately half of the patients experienced a change in one or more clinical symptoms, with differences observed between gender (e.g. day-to-day changes in slowness in men, aggravated headaches in women) and geographic location (e.g. increased depression in Alberta but reduced sleep quality in Québec). Furthermore, participants identifying as women or living in Alberta implemented more frequently home or online exercise. Lastly, high levels of satisfaction with phone or video consultations did not translate into a sustained interest to pursue this mode of healthcare. Conclusions This study suggests that COVID-19-related confinement affected Parkinson’s disease manifestation and management. Patients also reported varying levels of interest to continue remote care. A number of differences reported in our study were seemingly related to gender and living environment.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience

Jacquet¹,

Bogard²,

Normandeau³

et al. 2021

Parkinsonism & Related Disorders

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“…Moreover, approximately 40% of survey respondents reported changes in health, including a worsening of disease symptoms and weight gain. The extent of study respondents reporting a worsening in the physical and psychological domains of their health was similar to that found in other recent studies [13][14][15][16][17][18]31]. In our study, more than two-thirds of the respondents associated canceled rehabilitative care with a worsening of disease symptoms.…”

Section: The Effect Of Social Distancing and The Lockdown On Function Health Healthcare And Well-beingsupporting

confidence: 91%

“…Cumulative evidence from empirical studies supports some of these implications. For instance, studies have found evidence for reduced physical activity, worsening of motor and non-motor symptoms, difficulty acquiring neurology consultations or medications, increased anxiety, sleep disturbances, and increased burden on family members or caregivers [13][14][15][16][17][18]. In addition, associations have also been observed between the psychological impact of the COVID-19 pandemic and patients' background characteristics, such as disease severity, on reduced physical activity [14,15].…”

Section: Introductionmentioning

confidence: 99%

COVID-19 social distancing: negative effects on people with Parkinson disease and their associations with confidence for self-management

Yogev‐Seligmann

Kafri

2021

BMC Neurol

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Background The purpose of this study was to describe the effects of COVID-19 social distancing on the function, health, and well-being of people with Parkinson disease (PD), and test the association of these effects with patients’ activation levels, i.e., their skills and confidence in managing their health. Methods Community-dwelling individuals with PD answered an anonymous web-based survey. Part 1 included 27 multiple-choice questions regarding changes in function, health, medical care, and well-being. Part 2 consisted of the Patient Activation Measure, which enquired about skills and confidence in managing one’s health. Results Respondents (N = 142) reported decreases in various function (24.8%–37.3%), health (33.8%–43%), and well-being (26.1%–47.1%) domains. Rehabilitation ceased for 61.2%. Among those reporting a worsening of health, 67.8% associated this with the cessation of rehabilitative treatments or decrease in physical activity. Patients’ activation levels were inversely correlated with increased assistance for activities of daily living, increased tiredness, worsening symptoms, and lack of support from family and friends. Conclusions Social distancing had a major negative impact on the health and function of people with PD. Practical implications Supporting people with PD skills and confidence in managing health may preserve their physical and mental health during this period of dramatic changes in life’s circumstances.

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“…It is reasonable, however, to assume that people reduced their activity levels despite the lack of legal penalties in Japan for going out, 2 were staying in a confined space, 4,5 and experienced prolonged psychological stress, which may have exacerbated PD motor symptoms by reducing dopaminergic medication efficacy. 6,7 Alternatively, the worsening status during the pandemic may be related to disease progression, independent of reduced activity levels or psychological stress.…”

mentioning

confidence: 99%

Effects of the Coronavirus Disease 2019 Pandemic on Motor Symptoms in Parkinson's Disease: An Observational Study

et al. 2021

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It is becoming clear that many patients with Parkinson's disease (PD) are experiencing subjective worsening of motor symptoms during the coronavirus disease 2019 (COVID-19) pandemic. 1 However, little evidence using established quantitative scales is available on longitudinal changes in motor symptoms during the pandemic. We therefore evaluated changes in Movement Disorder Society Unified Parkinson's Disease Rating Scale, Part III (MDS-UPDRS-III), scores during the pandemic.We included PD patients who continuously visited the

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Impact of home confinement during COVID-19 pandemic on Parkinson's disease

Cited by 36 publications

References 6 publications

Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience

Clinical perception and management of Parkinson's disease during the COVID-19 pandemic: A Canadian experience

COVID-19 social distancing: negative effects on people with Parkinson disease and their associations with confidence for self-management

Effects of the Coronavirus Disease 2019 Pandemic on Motor Symptoms in Parkinson's Disease: An Observational Study

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