Impact of host gene polymorphisms on susceptibility to chronic hepatitis B virus infection

Arginase - 1 - Based Diagnosis as Indicator of the Risk of HBV - Related HCC

“…In addition, fibrosis and cirrhosis are inevitable complications of the infection, which leads to the death of a patient (3,4).…”

Evolution Revolution Life

“…There is a growing body of evidence of the role of various chemokine and chemokine receptor polymorphisms in different outcomes after infection with viruses, including HIV, HCV, and West Nile virus (11). Also, polymorphism of other immune system molecules, such as cytokines and pathogen-associated pattern recognition receptors, has an important role in determining the outcome of various infectious diseases (12)(13)(14). Importantly, major histocompatibility complex (MHC) molecules are the most polymorphic genes in vertebrates.…”

The CCR5-∆32 Mutation: Impact on Disease Outcome in Individuals with Hepatitis B Infection in the Southern Khorasan Population (East of Iran)

“…Evidence from previous studies proposed that host genetic factors, including a variety of immune cytokines and receptor genes, especially single nucleotide polymorphisms play a major role in determining immunization, clinical course, and recovery from HBV infection (9)(10)(11). chromosome 3.…”