Impact sur la survie de la procédure du ganglion sentinelle dans le cancer de la vulve : analyse de la SEER database

Canlorbe, Geoffroy; Rouzier, Roman; Bendifallah, Sofiane; Chéreau, E.

doi:10.1016/j.gyobfe.2012.07.014

Cited by 6 publications

(5 citation statements)

References 31 publications

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“…Nevertheless, this procedure is prone to complications such as lymphoedema, infection and scar disunions, which explains why practitioners are reluctant to perform it [4].…”

Section: Discussionmentioning

confidence: 99%

“…These risk factors for lymph node invasion are lesion size, depth of invasion, degree of differentiation, presence of vascular or lymphatic emboli, "perineural" invasion and clinical lymph node status. However, to date, there is no technique that can reliably predict inguinal lymph node invasion: palpation of the inguinal fossa has a sensitivity of 57% and a specificity of 62%, ultrasound of the inguinal fossa is operator-dependent, ultrasound-guided cytology is associated with too many false negatives, MRI cannot differentiate healthy from pathological lymph nodes by T1 and T2 sequences [10], magnetic resonance lymphography using Ultra Small Iron Oxide Particles (USIOP) is effective in detecting invaded nodes in penile cancer, but its application has not been demonstrated for vulvar cancer, nor has PET-CT [10].…”

Section: Discussionmentioning

confidence: 99%

“…The type of surgical excision depends on both the size of the lesion and the degree of deep infiltration, which dictate the treatment of lymph nodes [4].…”

Section: Introductionmentioning

confidence: 99%

“…The surgery is potentially morbid and disfiguring, with a high risk of scar disunion [3]. It is associated with a risk of major complications, including delayed healing, lymphorrhea and lymphedema, which impact on quality of life [4].…”

Section: Introductionmentioning

confidence: 99%

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Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Mariama,

Sakoba,

Abdoulaye

et al. 2024

OJOG

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Introduction: The aim of this study was to report the indications and evaluate the results of vulvectomy in the general surgery department of Ignace Deen Hospital, CHU Conakry. Materials and Methods: This was a retrospective descriptive study, conducted over a period of five (05) years from January 1, 2018 to December 31, 2022, in the general surgery department of Ignace Deen Hospital, CHU Conakry. We included in our study all patient records in whom vulvectomy was performed. Results: We recorded 15 cases of vulvectomy out of 453 perineal surgeries, i.e. 3.31%, with a mean age of 43.56 years and extremes of 35 and 69 years. Vulvar cancer was the most common diagnosis (46.67%), followed by Buschke-Lowenstein (33.33%) and anal canal cancer extending to the vulva (20%). Six patients had undergone biopsy (40%). Vulvectomy with lymph node dissection was performed in only 9 patients (60%), and all surgical specimens were sent to anatomical pathology (100%). Conclusion: Vulvectomy is a surgical technique most often indicated for the treatment of vulvar cancer.

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“…Nevertheless, this procedure is prone to complications such as lymphoedema, infection and scar disunions, which explains why practitioners are reluctant to perform it [4].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The type of surgical excision depends on both the size of the lesion and the degree of deep infiltration, which dictate the treatment of lymph nodes [4].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Mariama,

Sakoba,

Abdoulaye

et al. 2024

OJOG

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“…The rate of SLNB increased after 2008 following the publication of the results of the GROINSS-V-I 13 . A previous SEER study indicated that only 5.1% of patients received SLNB between 2004 and 2008 28 . It is still unclear why there are differences between the SLNB rate in our study and the studies by Rottmann et al .…”

Section: Discussionmentioning

confidence: 99%

Trends and Outcomes of Sentinel Lymph Node Biopsy in Early-stage Vulvar Squamous Cell Carcinoma: A Population-based Study

Zhou¹,

Zhang²,

Wu³

et al. 2018

J. Cancer

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Purpose: To compare trends and outcomes between lymphadenectomy and sentinel lymph node biopsy (SLNB) in node-negative early-stage vulvar squamous cell carcinoma (SCC) using a population-based cancer registry.Methods: Patients with vulvar SCC registered on the Surveillance, Epidemiology, and End Results program between 2003 and 2013 were identified. Statistical analysis was performed using Cox regression proportional hazards to calculate hazard ratio (HR) and 95% confidence interval (CI). A 1:1 propensity score matching (PSM) method was performed to minimize selection bias.Results: A total of 1475 patients were identified, including 1346 (91.3%) who received lymphadenectomy and 129 (8.7%) who underwent SLNB. The proportion of patients receiving SLNB increased between 2008 and 2013 compared with the years 2003-2007 (13.9% vs. 3.7%, p < 0.001). Five-year cause-specific survival (CSS) in patients who received lymphadenectomy and SLNB was 91.8% and 92.9%, respectively (p = 0.912), and 5-year overall survival (OS) was 77.5% and 82.5%, respectively (p = 0.403). SLNB was not associated with an decrease in CSS (HR 1.024, 95% CI 0.474-2.213, p = 0.952) or OS (HR 0.874, 95% CI 0.541-1.410, p = 0.581) in univariate and multivariate analyses. A total of 115 pairs were selected by PSM and survival analysis also showed comparable CSS (p = 0.481) and OS (p = 0.545) between lymphadenectomy and SLNB.Conclusions: There is an increasing trend toward SLNB in the treatment of patients with node-negative early-stage vulvar SCC, and survival is comparable between lymphadenectomy and SLNB.

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Sentinel Node Biopsy—Does It Help in the Management of Vulvar Cancer?

Oonk

Zee

Speiser

2013

Controversies in the Management of Gynecological Cancers

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Impact sur la survie de la procédure du ganglion sentinelle dans le cancer de la vulve : analyse de la SEER database

Cited by 6 publications

References 31 publications

Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Trends and Outcomes of Sentinel Lymph Node Biopsy in Early-stage Vulvar Squamous Cell Carcinoma: A Population-based Study

Sentinel Node Biopsy—Does It Help in the Management of Vulvar Cancer?

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