Impacto da vacina conjugada contra Streptococcus pneumoniae em doenças invasivas

Abstract

. Articles retrieved with the keywords Streptococcus pneumoniae, pneumococcal diseases, conjugate vaccine, antimicrobial resistance and meningitis were reviewed. Summary of the findings:The introduction of heptavalent pneumococcal conjugate vaccine caused a dramatic reduction in the incidence of invasive pneumococcal diseases in American children, reduced antibiotic use and the number of medical visits due to otitis media and pneumonia by children. The incidence of invasive pneumococcal diseases caused by resistant strains declined in immunized children, adults and elderly individuals. In Brazil, the mortality rate of pneumococcal meningitis is very high and the resistance to antibiotics has increased over the last 5 years.Conclusions: Heptavalent pneumococcal conjugate vaccine can benefit not only children, but the entire community and should be included in the Brazilian routine immunization schedule.J Pediatr (Rio J). 2006;82(3 Suppl):S67-74: Streptococcus pneumoniae, pneumococcal disease, conjugate vaccines, pneumonia, meningitis, antimicrobial resistance.