Ferrite nanoparticles have a significant impact in determining the dielectric behaviour and are promising materials for microwave and high frequency antenna applications. Thus chapter presents the frequency as well as temperature reliant dielectric properties of Mn 2+ doped Mg 0.5 Zn 0.5−x Mn x Fe 2 O 4 (where, x = 0.125, 0.250, 0.375, 0.500) nano-ferrites synthesized by co-precipitation. In comparison to that at higher frequencies, the dielectric constant falls dramatically at low frequencies. For every sample, the loss tangent was found to be minimal. The temperature reliant dielectric analysis of prepared samples reveals that the dielectric relaxation occurs at higher temperatures of approximately 531-667 K. The nano-ferrites being studied have minimal loss tangent values, making them potential candidates for microwave device applications.