Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A potential effect of non-pulmonary vein foci

Inden, Yasuya; Kato, Hiroyuki; Fujii, Aya; Mizutani, Yoshiaki; Ito, Tokiko; Kamikubo, Yasuhiko; Kanzaki, Yasunori; Ando, Motomi; Hirai, Makoto; Shibata, Rei; Murohara, Toyoaki

doi:10.1016/j.jjcc.2016.07.008

Cited by 32 publications

(29 citation statements)

References 24 publications

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“…However, we assume low success rates in patients with large LA diameters and thus we usually do not schedule patients with LA diameters > 55 mm for CB PVI. Reduced kidney function was recently detected as a predictor for AF recurrence [20], but was not significant in our cohort.…”

Section: Predictors For Af Recurrencecontrasting

confidence: 70%

Lessons from individualized cryoballoon sizing. Is there a role for the small balloon?

Hartl

Dorwarth

Bunz

et al. 2017

Journal of Cardiology

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Section: Predictors For Af Recurrencecontrasting

confidence: 70%

Lessons from individualized cryoballoon sizing. Is there a role for the small balloon?

Hartl

Dorwarth

Bunz

et al. 2017

Journal of Cardiology

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“…Glomerular filtration rate was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula [ 27 ] and a value <60 mL/min was considered a negative prognostic factor [ 28 ].…”

Section: Methodsmentioning

confidence: 99%

Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in Adult Patients at Nutritional Risk

et al. 2016

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Background: Elevated plasma vitamin B12 concentrations were identified as predictors of mortality in patients with oncologic, hepatic and renal diseases, and in elderly and critically ill medical patients. The association between vitamin B12 concentrations and in-hospital mortality in adult patients at nutritional risk has not been assessed. Methods: In this five-year prospective study, we investigated whether high vitamin B12 concentrations (>1000 pg/mL) are associated with in-hospital mortality in 1373 not-bed-ridden adult patients at nutritional risk (Nutrition Risk Index <97.5), admitted to medical and surgical departments. Results: Three hundred and ninety-six (28.8%) patients presented vitamin B12 > 1000 pg/mL. Two hundred and four patients died in the hospital (14.9%). The adjusted odds ratio of in-hospital mortality in patients with high vitamin B12 was 2.20 (95% CI, 1.56–3.08; p < 0.001); it was independent of age, gender, body mass index, six-month previous unintentional weight loss, admission ward, presence of malignancy, renal function, C-reactive protein and prealbumin. Patients with high vitamin B12 also had a longer length of stay (LOS) than those with normal concentrations (median 25 days, (IQR 15–41) versus 23 days (IQR 14–36); p = 0.014), and elevated vitamin B12 was an independent predictor of LOS (p = 0.027). Conclusions: An independent association between elevated vitamin B12 concentrations, mortality and LOS was found in our sample of hospitalized adult patients at nutritional risk. Although the underlying mechanisms are still unknown and any cause-effect relation cannot be inferred, clinicians should be aware of the potential negative impact of high vitamin B12 concentrations in hospitalized patients at nutritional risk and avoid inappropriate vitamin supplementation.

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“… 113 In a study of CKD patients undergoing cryoballoon ablation, patients with CKD G3 had significantly higher rates of AF recurrence compared with those with CKD G1 and G2. 114 No cases of contrast-induced nephropathy were reported. In general, sinus rhythm maintenance via ablation is associated with improved eGFR, while ablation failure is associated with eGFR decline.…”

Section: Rate Vs Rhythm Control Of Atrial Fibrillationmentioning

confidence: 99%

Chronic kidney disease and arrhythmias: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Turakhia

Blankestijn

Carrero

et al. 2018

European Heart Journal

223

146

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Impaired renal function is associated with recurrence after cryoballoon catheter ablation for paroxysmal atrial fibrillation: A potential effect of non-pulmonary vein foci

Abstract: Low eGFR at baseline was an independent predictor of recurrence after cryoballoon ablation for paroxysmal AF. The presence of non-PV ectopic beats was significantly increased in patients with impaired renal function, which might be associated with a poor outcome.

Cited by 32 publications

References 24 publications

Lessons from individualized cryoballoon sizing. Is there a role for the small balloon?

Lessons from individualized cryoballoon sizing. Is there a role for the small balloon?

Elevated Plasma Vitamin B12 Concentrations Are Independent Predictors of In-Hospital Mortality in Adult Patients at Nutritional Risk

Chronic kidney disease and arrhythmias: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

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