“…The use of ADM presents no significant increase of longterm complication rates and less capsular contracture compared to 2stage expander/im plant reconstruction without ADM (LoE 2b, C) [65]. Syn thetic meshes can be used in patients undergoing reconstruc tion after SSM or NSM with wellpreserved skin softtissue proportions and in patients with primary or secondary pro phylactic subcutaneous mastectomy; they seem to be a helpful tool for implant stabilization in terms of lateral stabilization and fixation of the musculus pectoralis major [66].…”
“…The use of ADM presents no significant increase of longterm complication rates and less capsular contracture compared to 2stage expander/im plant reconstruction without ADM (LoE 2b, C) [65]. Syn thetic meshes can be used in patients undergoing reconstruc tion after SSM or NSM with wellpreserved skin softtissue proportions and in patients with primary or secondary pro phylactic subcutaneous mastectomy; they seem to be a helpful tool for implant stabilization in terms of lateral stabilization and fixation of the musculus pectoralis major [66].…”
“…First clinical results show increased complications rates in patients undergoing secondary IBBR using TiLOOP Ò Bra [25]. In these secondary cases poor soft tissue conditions are frequently found.…”
Biochemical examination showed good biocompatibility for the investigated meshes and matrix. All products seem to have their value in IBBR and can be recommended for IBBR.
“…As continuing advancements in technology and bioprosthetic design are realized, different implant characteristics and nonhuman acellular dermal matrix may illustrate improved cost efficacy, which has yet to be explored adequately. 12,42,53,54 Similarly, patient-reported outcomes and quality of life are quickly growing foci in health care outcomes research. Incorporating these aspects in reconstructive modality comparisons is vital to optimizing patient outcomes.…”
Section: Limitations and Future Considerationsmentioning
Although direct-to-implant and two-stage tissue expander/implant reconstruction are successful approaches, this meta-analysis demonstrates significantly greater risk of flap necrosis and implant failure with direct-to-implant reconstruction. The authors' findings suggest that the critical component of patient selection is judgment of mastectomy flap tissue quality. These findings can enhance the risk counseling process and highlight the need for additional investigations to optimize outcomes.
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