“…Considering the craniofacial district, the most common anatomical features are maxillary hypoplasia, mandibular protrusion, midface depression, reduced facial height, frontal bulging, abnormal or missing sweat glands, hypotrichosis, dry skin, protuberant lips, saddle nose (6)(7). Furthermore, oral manifestations are also frequently observed including hypodontia, defective enamel, peg shaped teeth, delayed dental eruption and severe alveolar ridge deficiency (8). Hypodontia is the most frequently found sign of oral anomalies, with an estimated prevalence of 80% in ED patients (9)(10)(11).…”