Implementation of Multichannel Sensors for Remote Biomedical Measurements in a Microsystems Format

Johannessen, Erik; Wang, Lei; Li, Cui; Tang, Tong Boon; Ahmadian, M.; Astaras, A.; Reid, S. W. J.; Yam, P.S.; Murray, Alan F.; Flynn, Brian; Beaumont, S. P.; Cumming, David R. S.; Cooper, Jonathan M.

doi:10.1109/tbme.2003.820370

Cited by 115 publications

(51 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition to physiological parameters, such as intraluminal pH, temperature, and pressure, the whole and regional gastrointestinal transit times (GITT) are a useful measure for diagnosing these gastric disorders. The first demonstration of a truly multisensing capsule (16 mm 9 55 mm) was presented in 2004 by Johannessen et al 45 who showed in vitro measurements of pH, temperature, dissolved oxygen, and conductivity. Since clearing FDA approval in 2006, Given Imaging markets the SmartPill â capsule technology, which determines gastric motility and GITT by measuring and recording pH, pressure, and temperature.…”

Section: A2 Physiological Sensing and Therapeuticsmentioning

confidence: 99%

Magnetically guided capsule endoscopy

et al. 2017

View full text Add to dashboard Cite

Wireless capsule endoscopy (WCE) is a powerful tool for medical screening and diagnosis, where a small capsule is swallowed and moved by means of natural peristalsis and gravity through the human gastrointestinal (GI) tract. The camera-integrated capsule allows for visualization of the small intestine, a region which was previously inaccessible to classical flexible endoscopy. As a diagnostic tool, it allows to localize the sources of bleedings in the middle part of the gastrointestinal tract and to identify diseases, such as inflammatory bowel disease (Crohn's disease), polyposis syndrome, and tumors. The screening and diagnostic efficacy of the WCE, especially in the stomach region, is hampered by a variety of technical challenges like the lack of active capsular position and orientation control. Therapeutic functionality is absent in most commercial capsules, due to constraints in capsular volume and energy storage. The possibility of using body-exogenous magnetic fields to guide, orient, power, and operate the capsule and its mechanisms has led to increasing research in Magnetically Guided Capsule Endoscopy (MGCE). This work shortly reviews the history and state-of-art in WCE technology. It highlights the magnetic technologies for advancing diagnostic and therapeutic functionalities of WCE. Not restricting itself to the GI tract, the review further investigates the technological developments in magnetically guided microrobots that can navigate through the various air-and fluid-filled lumina and cavities in the body for minimally invasive medicine.

show abstract

Section: A2 Physiological Sensing and Therapeuticsmentioning

confidence: 99%

Magnetically guided capsule endoscopy

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Polyetheretherketones (PEEK) was used for the biocompatible housing, as it is very easy to machine and its biocompatible characteristics are well established [9,10]. The housing thickness (0.8 mm) was selected to improve the electromagnetic radiation of the implanted radiator in agreement with the results reported in [11].…”

Section: Body Sensor Nodementioning

confidence: 99%

In Vitro and In Vivo Operation of a Wireless Body Sensor Node

Merli

Bolomey

Gorostidi

et al. 2012

Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering

View full text Add to dashboard Cite

show abstract

“…These comprise two temperature, two ISFET pH, two conductivity, and two dissolved oxygen sensors, providing channel redundancy. Two different bio-MEMS sensor chips were implemented [17]. One comprised a silicon diode temperature sensor, an ISFET pH sensor and a two-electrode conductivity sensor; the second chip had an oxygen sensor.…”

Section: A Sensor Circuitmentioning

confidence: 99%

A Programmable Microsystem Using System-on-Chip for Real-time Biotelemetry

Wang

Johannessen

Hammond

et al. 2005

IEEE Trans. Biomed. Eng.

Self Cite

View full text Add to dashboard Cite

Abstract-A telemetry microsystem, including multiple sensors, integrated instrumentation and a wireless interface has been implemented. We have employed a methodology akin to that for System-on-Chip microelectronics to design an integrated circuit instrument containing several "intellectual property" blocks that will enable convenient reuse of modules in future projects. The present system was optimized for low-power and included mixed-signal sensor circuits, a programmable digital system, a feedback clock control loop and RF circuits integrated on a 5 mm 5 mm silicon chip using a 0.6 m, 3.3 V CMOS process. Undesirable signal coupling between circuit components has been investigated and current injection into sensitive instrumentation nodes was minimized by careful floor-planning. The chip, the sensors, a magnetic induction-based transmitter and two silver oxide cells were packaged into a 36 mm 12 mm capsule format. A base station was built in order to retrieve the data from the microsystem in real-time. The base station was designed to be adaptive and timing tolerant since the microsystem design was simplified to reduce power consumption and size. The telemetry system was found to have a packet error rate of 10 3 using an asynchronous simplex link. Trials in animal carcasses were carried out to show that the transmitter was as effective as a conventional RF device whilst consuming less power.

show abstract

Implementation of Multichannel Sensors for Remote Biomedical Measurements in a Microsystems Format

Cited by 115 publications

References 29 publications

Magnetically guided capsule endoscopy

Magnetically guided capsule endoscopy

In Vitro and In Vivo Operation of a Wireless Body Sensor Node

A Programmable Microsystem Using System-on-Chip for Real-time Biotelemetry

Contact Info

Product

Resources

About