“…Several tools are employed in green analytical chemistry to study the environmental performance of an analytical procedure, including the Analytical Eco-Scale tool, the National Environmental Methods Index (NEMI), the Green Analytical Procedure Index (GAPI), the Analytical Greenness (AGREE) tool, and the newer Analytical Greenness Metric for Sample Preparation (AGREEprep) tool. Objective criteria related to analytical performance, environmental impact, sustainability, and economic cost are evaluated by these tools through the definition of penalty points [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 ]. This makes it possible to choose the most environmentally friendly analytical procedure, which is very important nowadays for both ecological and also economic and analytical reasons.…”