Z-pinches have been explored as efficient soft x-ray sources for many years. To optimize x-ray emission, various z-pinch configurations were tested. This paper presents data obtained with a hybrid gas-puff z-pinch imploding onto on-axis wires on a microsecond, multi-megaampere GIT-12 generator. In our previous experiments, the hybrid gas puff, i.e., an inner deuterium gas puff surrounded by an outer hollow cylindrical plasma shell, was used to produce energetic protons, deuterons, and neutrons up to 60 MeV [Klir et al., New J. Phys. 22, 103036 (2020)]. The behavior of the hybrid gas-puff z-pinch on GIT-12 was interpreted as a high-density plasma opening switch with a microsecond conduction time, 3 MA conduction current, nanosecond opening, and up to 60 MV stand-off voltage. These properties can be employed to transfer the current into an on-axis load with a high rise rate. In the recent experiments on GIT-12, we therefore placed single or multiple aluminum wires on the axis of the hybrid gas-puff z-pinch. Before a current sheath arrived at the axis, a coronal plasma was seen around the wire. A rapid increase in x-ray radiation was observed when the coronal plasma imploded onto the axis. The coronal plasma implosion resulted in a long (2 cm), narrow (∼mm) column radiating in the Al K-shell lines. With the single Al wire of 80 μm diameter, the K-shell x-ray output reached 5.5 ± 0.8 kJ in a 0.6 ± 0.1 TW peak power and 7 ± 1 ns pulse. The higher K-shell yield of 12 ± 2 kJ and peak K-shell power of 0.7 ± 0.1 TW were achieved with four 38 μm diameter Al wires. (Their cross section formed the corners of a square with 1 mm side.) The presence of the wires on the axis significantly suppressed ion acceleration and neutron production. Deuterium-deuterium (DD) neutron yields of about 1.2 × 1011 were 20 times smaller than the yields produced in shots without any wire. The DD neutron yield was increased up to 4.5 × 1011 when the Al wire was replaced by a fiber from deuterated polyethylene. A characteristic feature of the experiments with the (CD2)n fiber was a rapid expansion with the velocity approaching 900 km/s.