2023
DOI: 10.13005/bpj/2679
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Improved Antibiotic Activity from Streptomyces monomycini strain RVE129 Using Classical and Statistical Design of Experiments

Abstract: Many bioactive secondary metabolites with intriguing antibacterial, antiviral, and anticancer properties have been produced by Streptomyces species. The objective of this work is to use conventional and statistical techniques to improve the antibiotic production medium of Streptomyces monomycini RVE129, which was isolated from rhizospheric soil in Hawassa, Ethiopia. The main media components were chosen using the one factor at a time method and the Plackett-Burman design, which was then, further, optimized usi… Show more

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