Improved design and experimental demonstration of a bi-directional microfluidic driving system

Jen, Chun-Ping; Lin, Yu-Cheng; Wu, Wei-Da; Wu, Chung-Yi; Wu, Guang-Guo; Chang, Chong-Ching

doi:10.1016/s0925-4005(03)00553-7

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Cited by 4 publications

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“…through microchannels (99). A liquid driving system without moving parts or electrodes that is based on suction and exclusion generated by a stable airflow was presented by Jen et al (100).…”

Section: Technologiesmentioning

confidence: 99%

Micro Total Analysis Systems. Recent Developments

2004

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Section: Technologiesmentioning

confidence: 99%

Micro Total Analysis Systems. Recent Developments

2004

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“…This design can be integrated with a bi-directional pumping device. 20,21 Based on the above concept, two micromixers (M1 and M2) were designed as shown in Fig. 2.…”

Section: Device Design and Experimental Setupmentioning

confidence: 99%

Design of passive mixers utilizing microfluidic self-circulation in the mixing chamber

et al. 2004

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This paper proposes the design of a passive micromixer that utilizes the self-circulation of the fluid in the mixing chamber for applications in the Micro Total Analysis Systems (microTAS). The micromixer with a total volume of about 20 microL and consisting of an inlet port, a circular mixing chamber and an outlet port was designed. The device was actuated by a pneumatic pump to induce self-circulation of the fluid. The self-circulation phenomenon in the micromixer was predicted by the computational simulation of the microfluidic dynamics. Flow visualization with fluorescence tracer was used to verify the numerical simulations and indicated that the simulated and the experimental results were in good agreement. Besides, an index for quantifying the mixing performance was employed to compare different situations and to demonstrate the advantages of the self-circulation mixer. The mixing efficiencies in the mixer under different Reynolds numbers (Re) were evaluated numerically. The numerical results revealed that the mixing efficiency of the mixer with self-circulation was 1.7 to 2 times higher than that of the straight channel without a mixing chamber at Re= 150. When Re was as low as 50, the mixing efficiency of the mixer with self-circulation in the mixing chamber was improved approximately 30% higher than that in the straight channel. The results indicated that the self-circulation in the mixer could enhance the mixing even at low Re. The features of simple mixing method and fabrication process make this micromixer ideally suitable for microTAS applications.

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