Improved Differentiation of Benign and Malignant Lymphadenopathy in Patients With Cutaneous Melanoma by Contrast-Enhanced Color Doppler Sonography

Schmid‐Wendtner, Monika‐Hildegard; Partscht, Karin; Körting, Hans Christian; Volkenandt, Matthias

doi:10.1001/archderm.138.4.491

Cited by 43 publications

(33 citation statements)

References 19 publications

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“…The most often used classification is that of Tschammler and colleagues, 25 who found lymph nodes with a pulsatility index of 1.8 or more and a resistive index of 0.9 or more to be suggestive of malignancy. In our own patients with melanoma, the pulsatility index and resistive index values were disappointing in their ability to separate malignant from benign lymph nodes 21 ; Moehrle and coworkers 26 have reported the same problem. These qualitative vascular patterns are difficult to detect in very small lymph node metastases, for example, those located in the margin of a reactive lymph node (Figure 8).…”

Section: Native and Signal-enhanced Cdsmentioning

confidence: 84%

“…In such cases, further diagnostic steps including the evaluation of vascular patterns in suspect peripheral lymph nodes by native or signalenhanced CDS can be helpful. 20,21 Involvement of the peripheral lymph nodes in malignant lymphomas does not have a uniform sonographic picture. In many patients, hypoechoic enlarged masses can be demonstrated by B-mode sonography.…”

Section: Assessment Of Lymph Nodes By 75-to 10-mhz Sonographymentioning

confidence: 99%

“…28,29 Levovist has been tried in a pilot study in patients with melanoma to improve visualization of the vascularization pattern in lymphadenopathy, for which it provided additional discriminatory information. 21 Although signal-enhanced CDS is not recommended as a routine diagnostic method, it may be helpful in small lymph nodes with uncertain results by B-scan examination and native CDS, especially to help prevent unnecessary surgery for small reactive lymph nodes (Figure 9).…”

Section: Native and Signal-enhanced Cdsmentioning

confidence: 99%

See 2 more Smart Citations

Ultrasound Scanning in Dermatology

Schmid‐Wendtner¹,

Burgdorf²

2005

Arch Dermatol

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138

128

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Section: Native and Signal-enhanced Cdsmentioning

confidence: 84%

Section: Assessment Of Lymph Nodes By 75-to 10-mhz Sonographymentioning

confidence: 99%

Section: Native and Signal-enhanced Cdsmentioning

confidence: 99%

See 1 more Smart Citation

Ultrasound Scanning in Dermatology

Schmid‐Wendtner¹,

Burgdorf²

2005

Arch Dermatol

Self Cite

138

128

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“…Spectral Doppler imaging is time-consuming and requires detection of vessels of sufficient caliber. Additionally, Schmid-Wendtner et al 29 have shown a significant overlap between the Doppler spectra of benign and malignant lymph nodes in patients with melanoma.…”

mentioning

confidence: 99%

Sonography for Locoregional Staging and Follow-up of Cutaneous Melanoma

Catalano

Setola

Vallone

et al. 2010

Journal of Ultrasound in Medicine

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Objective. Sonography is being used with increasing frequency in the assessment of locoregional tumor spread in patients with melanoma. Nevertheless, to maximize its practical impact, sonography should be performed with state-of-the-art equipment, by specifically trained operators, and using a careful exploration technique and well-defined diagnostic criteria. In this "how I do it"-type article, we illustrate our practical approach to sonography of cutaneous melanoma. Methods. We first illustrate the basic and advanced technical requirements; then we describe our exploration methods and our image interpretation approach; and finally, we report on our use of sonography as a guidance tool for interventional procedures. Special emphasis is given to methodological and interpretative clues, tricks, and pitfalls. Results. Sonography can be used in the initial staging of patients with melanoma, particularly in the screening of patients scheduled for a sentinel lymph node biopsy procedure. Additionally, sonography can be used during patient follow-up to detect locoregional recurrence earlier than palpation. Conclusions. Sonography plays a growing role in the assessment of the superficial spread of melanoma. Nevertheless, state-of-the-art equipment and careful exploration by trained operators are necessary.

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“…Neben dem bereits etablierten Einsatz der dopplersonographischen Verfahren [9,19] ist zu erwarten, dass die Fortentwicklung der Gerätetechnologie und -software, aber auch der Einsatz neuer Methoden wie des kontrastmittelverstärkten Ultraschalls [20] die diagnostischen Möglichkeiten der sonographischen Metastasendetektion weiter verbessern.…”

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