Improved separation with the intermittently pressed tubing of multilayer coil in type-I counter-current chromatography

Yang, Yi; Yang, Jiao; Chen, Fang; Wang, Jihui; Gu, Dongyu; Tian, Jing; Ito, Yoichiro

doi:10.1016/j.chroma.2018.03.052

Cited by 4 publications

(1 citation statement)

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“…MDCCC involves integrating CCC with other separation techniques, like high-performance liquid chromatography (HPLC), mass spectrometry (MS), and gas chromatography (GC). The CCC method is a useful preparative chromatographic instrument that complements HPLC due to its high selectivity and good retention of the stationary phase, even though HPLC's efficiency (regarding theoretical plate number) outclasses it [5,6].…”

Section: Introductionmentioning

confidence: 99%

Recent trends in multidimensional countercurrent chromatography

Muhire,

Sun,

Zhang

et al. 2024

J of Separation Science

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Countercurrent chromatography (CCC) is a potent separation approach known for its remarkable efficiency and capacity in preparation. It's applied as a substitute or combined with different chromatographic techniques, resulting in its rebranding as multidimensional CCC (MDCCC). Numerous essential mixtures from natural products contain hundreds or thousands of distinct components of importance. These mix types are too complicated to separate in any reasonable time using a single CCC dimension. However, if a multidimensional technique is utilized, where a complex mixture is separated by an initial dimension, smaller fractions of that separation are gathered. Each fraction is studied individually; complex mixes can be resolved relatively quickly. Thus, several MDCCC separation features have been studied to demonstrate their advantages, limitations, and prospective capacity to separate exceedingly complex mixtures. In this review, MDCCC aspects, including principles, multiple columns system, multilayer coil J‐type, on‐line monitoring system, and applications, have been thoroughly_explored.

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Section: Introductionmentioning

confidence: 99%