Improvement in phloroglucinol compound extracted from different parts of <i>Eugenia umbelliflora</i> monitored by LC-UV and antimicrobial activity

Farias, Ingrid Vicente; Amorim, Clarissa M.; E, Graff; Breia, Isabel; Santos, Matheus Corrêa dos; Norberto, Silvana; Faqueti, Larissa; Bresolin, Tania Mari Bellé; Cruz, Alexandre Bella; Meyre‐Silva, Christiane

doi:10.1080/14786419.2020.1868458

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Respiratory Syncytial Virus1

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Cited by 3 publications

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“…Both compounds reduced the expression of respiratory (human) syncytial virus F proteins (RSV F proteins) with an IC50 of 6. 75 62) and (-)rhodomyrtone (63) (Figure 8). Both the compounds were active against RSV, showing IC50 values of 3.00 μM and 0.39 μM, respectively (56).…”

Section: Respiratory Syncytial Virusmentioning

confidence: 99%

Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest

Peron

López

Cabada-Aquirre

et al. 2023

Critical Reviews in Biotechnology

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Section: Respiratory Syncytial Virusmentioning

confidence: 99%

Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest

Peron

López

Cabada-Aquirre

et al. 2023

Critical Reviews in Biotechnology

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Anti-inflammatory and Antioxidant Activity of Eugenial D from Eugenia astringens

Barreta,

Bramorski,

Knecht

et al. 2024

Rev. Bras. Farmacogn.

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In Vitro Antioxidant and Anti-inflamatory Activty of a Eugenia Umbellflora Phloroglucinol

Barreta,

Bramorski,

Knecht

et al. 2023

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Eugenia umbelliflora is a plant widely used in the Brazilian traditional medicine due to its anti-inflammatory and antibacterial properties. Its fruits are an important natural source of phloroglucinols such as eugenial D. In this study, the in vitro antioxidant and anti-inflammatory activity of this compound was investigated, which was isolated from the methanol extract of E. umbelliflora unripe fruits. The antioxidant activity was evaluated by DPPH, ORAC, ABTS and metal chelating activity assays whereas. The anti-inflammatory activity through the nitric oxide inhibitory assay. The results demonstrated a pro-oxidant effect of the eugenial D due to its ability to neutralize ROS species and metal ions as well as significant in vitro anti-inflammatory activity (inhibited 58.65% of NOx production at 1 µM). A very low cytotoxicity was also identified (CC50 higher than 348µM), suggesting a selectivity of action.

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Improvement in phloroglucinol compound extracted from different parts of Eugenia umbelliflora monitored by LC-UV and antimicrobial activity

Cited by 3 publications

References 8 publications

Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest

Antiviral and antibacterial properties of phloroglucinols: a review on naturally occurring and (semi)synthetic derivatives with potential therapeutic interest

Anti-inflammatory and Antioxidant Activity of Eugenial D from Eugenia astringens

In Vitro Antioxidant and Anti-inflamatory Activty of a Eugenia Umbellflora Phloroglucinol

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