Abstract:There are approximately 500,000 neonatal patients in the United States requiring neonatal intensive care annually. 1 Cruz et al 2 determined that the hospitalized neonate experiences between 7 and 17 painful procedures per day, with premature infants experiencing the highest number daily. The landmark article by Anand and Hickey 3 described evidence, suggesting physiologic responses to painful stimuli in neonates of various gestational ages are reflected in hormonal, metabolic, and cardiorespiratory changes. … Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.