Improving Vaccine Safety by Using an Algorithmic Model as a Replacement for a Physical Thermal Buffer

Rusnack, Michael Richard

doi:10.24926/iip.v9i1.962

Cited by 2 publications

(3 citation statements)

References 2 publications

(2 reference statements)

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“…Furthermore, in practice, vaccines and thermometer probes should not be placed in drawers, on the floor, next to walls, indoors, and near the outlet of cold air from the freezer as the temperature is very likely to differ significantly from the inside of the storage unit and the vaccine ( Long and Hayney, 2013 ). Therefore, the thermometer probe needs to be inserted into a glycol vial or another equivalent thermal buffer medium ( Rusnack, 2018 ). Such thermal buffers are intended to reduce false alarms hence field personnel is determined with greater confidence that a warning is an event that requires action.…”

Section: Latest Inventions and Innovationsmentioning

confidence: 99%

“…Although this method theoretically promises accuracy, data reading errors often occur in practice. Therefore, to overcome this problem, Rusnack (2018) developed an algorithm for measuring temperature in vaccines to increase their accuracy ( Rusnack, 2018 ). Furthermore, Clénet (2018) developed a multiple-month model of forced degradation with high accuracy results for the measurement of time and temperature profiles ( Clénet, 2018 ).…”

Section: Latest Inventions and Innovationsmentioning

confidence: 99%

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Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

et al. 2022

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The outbreaks of infectious diseases that spread across countries have generally existed for centuries. An example is the occurrence of the COVID-19 pandemic in 2020, which led to the loss of lives and economic depreciation. One of the essential ways of handling the spread of viruses is the discovery and administration of vaccines. However, the major challenges of vaccination programs are associated with the vaccine cold chain management and cold storage facilities. This paper discusses how vaccine cold chain management and cold storage technology can address the challenges of vaccination programs. Specifically, it examines different systems for preserving vaccines in either liquid or frozen form to help ensure that they are not damaged during distribution from manufacturing facilities. Furthermore, A vaccine is likely to provide very low efficacy when it is not properly stored. According to preliminary studies, the inability to store vaccine properly is partly due to the incompetency of many stakeholders, especially in technical matters. The novelty of this study is to thoroughly explore cold storage technology for a faster and more comprehensive vaccine distribution hence it is expected to be one of the reference and inspiration for stakeholders.

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Section: Latest Inventions and Innovationsmentioning

confidence: 99%

Section: Latest Inventions and Innovationsmentioning

confidence: 99%

Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

et al. 2022

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“…Demonstrated in an independent study, the accurate derivation of the constant k results in a much more accurate representation of the temperature of the stored contents with an error of .5%. (Rusnack, 2018) . With the ability to represent the temperature of the stored goods, while providing an equivalency of buffering the air temperature, it is no longer necessary to utilize a physical buffer.…”

Section: Equation 3 -Algorithmic Buffer Equationmentioning

confidence: 99%

Errors That Occur from Using an Inappropriate Thermal Buffer When Monitoring the Storage Conditions of Temperature Sensitive Products: Size and Material DO Matter

Rusnack¹

2018

Innov Pharm

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Common practice in the monitoring of cold chain conditions for temperature sensitive products is to employ a physical thermal buffer into which the temperature probe is inserted. This buffer may be a bottle of glycol or other liquid, a container of glass beads, aluminum block or nearly any other media the user feels appropriate. The purpose of the buffer is to simulate the experience of the stored product rather than the air temperature. Obviously, this mission will not be accomplished to the extent that the physical buffer is not matched to the thermal properties of the stored product and its container. Cold chain managers are faced with a complex problem if they attempt to take this issue into account. Furthermore, a match is not possible with a single physical buffer when the cold storage unit contains different products or size containers. This paper quantifies the results of this mismatch from various factors and suggests possible solutions to this dilemma. Type: Original Research

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Improving Vaccine Safety by Using an Algorithmic Model as a Replacement for a Physical Thermal Buffer

Abstract: Conventional practice in vaccine storage is to insert a temperature probe into

Cited by 2 publications

References 2 publications

Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

Vaccine cold chain management and cold storage technology to address the challenges of vaccination programs

Errors That Occur from Using an Inappropriate Thermal Buffer When Monitoring the Storage Conditions of Temperature Sensitive Products: Size and Material DO Matter

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