In vitro Anthelmintic Activity of Leaf Extracts of Adhatoda vasica Nees (Acanthaceae) Against Eudrilus eugeniae

Bhinge, Somnath D.; Desai, Prachi; Magdum, C. S.

doi:10.3329/dujps.v14i2.28504

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…Bark of Lodhra has flavanol, glucosides, and oleanolic acid which is why it is used for treating antibacterial infections and parasitic infections [39]. Patha is used for treating angina, breathing problems and worm infections.…”

Section: Chandansavamentioning

confidence: 99%

Pharmacological Potential of Polyherbal Ayurvedic Formulations – A Review

NATH¹,

Awasthi²,

K³

et al. 2022

Asian J Pharm Clin Res

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Ayurveda is an ancient traditional medical care system. The major aim of Ayurveda is to prevent unnecessary suffering and aiding healthy long life. Ayurveda incorporates natural constituents to make potential medicines that are believed to eliminate the root cause of the diseases. Forty-five thousand plant species are found in the subcontinent of India making it one of the largest biodiversity centers. In India alone, 15,000 medicinal plant species have been reported out of which 7500 species are used by the communities to cure different diseases. Ayurveda uses single or polyherbal for treatment. In these traditional medicine systems, various formulations are prepared one of which is fermented formulations, namely, arishtas and asavas. These formulations are prepared using a decoction of herbal drugs and contain self-generated alcohol. Fermented formulations are known for their stability and efficacy. Indian traditional literature states the usage of these formulations regularly with scientific validation strengthens one immunity and well-being. The current review focuses on Vidangarishta. Punarnavasava, Chandanasava, their preparations, therapeutics uses, and their toxic effects. A thorough understating of these formulations aids in standardizing Ayurveda as a marginalized medicine.

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Section: Chandansavamentioning

confidence: 99%

Pharmacological Potential of Polyherbal Ayurvedic Formulations – A Review

NATH¹,

Awasthi²,

K³

et al. 2022

Asian J Pharm Clin Res

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“…The anthelmintic activity leaf and seed extract of Cassia Occidentalis, were carried at different concentrations (10, 20, and 50 mg/mL) by following the method of Bhinge et al, (2015) with minor variations. Before starting the procedure all the solutions were freshly prepared.…”

Section: Anthelmintic Activity Screeningmentioning

confidence: 99%

Phytochemical screening and anthelmintic activity of leafand seed extract of Cassia occidentelis L.

Khan¹

2021

Eurasian Journal of Biological and Chemical Sciences

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In present study the ethanolic extracts of leaf and seed of Cassia occidentalis were investigated for their phytochemical properties and anthelmintic activity against Haemonchus controtus at different concentrations (100, 150, 200 mg/ml). Alkaloids, flavonoids, saponins, tannins, phenols, steroids and carbohydrates are present in both leaf and seeds crude extracts. The study is mainly concerned with the determination of time of paralysis and time of death of the worms. When there was a gradual increase in the dose, a gradual increase in the anthelmintic activity was observed. The least time for the death and paralysis was recorded at concentration of 50 mg/mL and maximum time for death and paralysis was recorded at 10mg/mL concentration. The ethanolic extract of the leaf and seed showed a significant anthelmintic activity at highest concentration of 50 mg/ml. So the C. occidentalis plant can be used as anthelmintic drug for the treatment of gastrointestinal helminthic infections after clinical trials, toxicological effects and isolation of chemical compounds.

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“…properties like anthelmintic, antiulcer, anticestodal, antioxidant, antifungal, antimicrobial and antibacterial effect [27][28][29]. Piper betle and Pongamia pinnata have been known to possess various therapeutic properties like antioxidant, antifungal, antimicrobial, hypoglycemic and antibacterial effect [30][31][32][33][34][35][36].…”

mentioning

confidence: 99%

Formulation and evaluation of polyherbal gel containing extracts of Azadirachta indica, Adhatoda vasica, Piper betle, Ocimum tenuiflorum and Pongamia pinnata

Bhinge¹,

Bhutkar²,

Randive³

et al. 2018

jrp

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In the Indian system of medicine-Ayurveda, azadirachta indica, adhatoda vasica, piper betle, ocimum tenuiflorum and pongamia pinnata has been mentioned as a remedy for treatment of various infectious diseases and ailments. Based on the folkloric use, the present study was designed to formulate and evaluate polyherbal gel containing extracts of Azadirachta indica, Adhatoda vasica, Piper betle, Ocimum tenuiflorum and Pongamia pinnata. Gel formulations (Formulation A, B and C) were prepared which comprised of the ethanolic extracts of Azadirachta indica, Adhatoda vasica, Piper betle, Ocimum tenuiflorum and Pongamia pinnata in a concentration of 0.1, 0.3 and 0.5 %, respectively in a base. The prepared formulations were evaluated for appearance and homogeneity, pH, viscosity and rheological studies, spreadability, skin irritation test (patch test) and washability. The formulations were also screened for their antimicrobial activity by disc plate method against S. aureus, B. subtilis, A. niger and E. coli. The results of the studies revealed that all formulations under study viz. A, B and C showed better zone of inhibition as compared with the control. However, formulation C exhibited maximum activity against the selected strains which may be attributed to its greater amount of herbal extracts as compared to formulation A and B. The polyherbal gel formulations were observed to possess antimicrobial action. The effective activity may be attributed to the synergistic action of the plants constituents present in the formulation.

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In vitro Anthelmintic Activity of Leaf Extracts of Adhatoda vasica Nees (Acanthaceae) Against Eudrilus eugeniae

Cited by 3 publications

References 12 publications

Pharmacological Potential of Polyherbal Ayurvedic Formulations – A Review

Pharmacological Potential of Polyherbal Ayurvedic Formulations – A Review

Phytochemical screening and anthelmintic activity of leafand seed extract of Cassia occidentelis L.

Formulation and evaluation of polyherbal gel containing extracts of Azadirachta indica, Adhatoda vasica, Piper betle, Ocimum tenuiflorum and Pongamia pinnata

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